Hello,
Considering the results of an article which is similar to my current research, in a validated Soxhlet extraction method, the ratio of solvent to herbal powder should be 21.78 (v/w). But because of the small amount of the herbal powder and the large size of the apparatus that I have, it is not possible to follow this instruction.
I am wondering if using the same recommended solvent --but in a larger amount than the recommended volume-- while maintaining the same recommended duration of time of extraction can alter the efficiency of the extraction process.
I would appreciate it if you could help me with this question.
Check http://www.scienceasia.org/2009.35.n3/scias35_306.pdf
Also check https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/soxhlet-extraction
Kindly check this paper.
https://www.mdpi.com/2227-9717/8/10/1222/pdf
Hello,
you may increase the amount of solvent without any significant alteration of the extraction efficiceny. But afterwards you will have more work, i.e. you need more time to reduce the volume or to remove the solvent, respectively.
Kind regards, KPL
It depends on the chemical classes in the plant you extract. You may extract excessiv, non_desired compounds when using too much of solvent because you decrease solvation power for other less extrable cmpds.
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