Dear all,

It is well known that matching can increase the statistical power of the study if the matching variable is a strong confounder that is strongly related to both 1) exposure and 2) outcome. So, as expected, no statistical power is gained if the matching variable is a weak confounder.

In detail, 1) if the matching variable is slightly or not related to exposure, but is strongly related to the outcome, very small statistical power is gained. While, 2) if the matching variable is slightly or not related to the outcome, but is strongly related to the exposure, statistical power may even be reduced.

I do not know the reason for the last sentence. According to the articles "https://doi.org/10.1093/biomet/68.3.577" and "https://doi.org/10.1093/oxfordjournals.aje.a113475", I have made a series of assumptions; however, I need some further clarification.

I would be grateful if you kindly let me know your opinions.

Kind regards,

More Seyedeh Elaheh Bagheri's questions See All
Similar questions and discussions