The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and... | Contact experts in Solubility to get answers
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Questions related to Solubility
I am working on phase solubility studies between beta-cyclodextrin and drug? I used more concentration of beta-cyclodextrin till 30mM despite its maximum solubility of 16mM. Usually, above maximum...
31 October 2020 4,059 9 View
I have tried injecting my gas samples manually into GC equipped with TCD and FID using a gas tight syringe for the analysis of products. I found that FID gives a higher peak for CO as compared to...
30 October 2020 2,971 12 View
Hi All, I have several trials for few months to extract good genomic DNA from some cultures of Asp. nidulans, most of them worked with CTAB extraction from freez-dried mycelium (30-40-60 hrs old)...
22 October 2020 6,163 3 View
I'm trying to make Nanostructured lipid carriers (NLC) using ultrasonicator method for cancer meds that are hydrophobic and insoluble in water. I'm heating solid and liquid lipid phase and then...
22 October 2020 9,194 5 View
Does Li2CO3 solubility in water depends on the ph of the water?? And if it does, pH increase makes Li2CO3 solubility low?? I wanted to search the data, but I couldn't found it. Please answer...
20 October 2020 3,149 3 View
I am looking to dissolve a suite of "acidic" peptides for, ultimately, a validated LCMS assay. Using DMF as an initial solvent (20% of final volume) but some peptides precipitate when aqueous is...
16 October 2020 9,327 1 View
I know that PLA is soluble in DCM, not soluble in water and hard to dissolve in DMF. What kind of solvents will be suitable for electrospray system for the amphiphilic polysaccharide and...
14 October 2020 3,633 4 View
For dissolving haloalkanes which is best solvent - polar or nonpolar? How much quantity of solvent is required if the solublity is unknown.
13 October 2020 3,631 4 View
Dear Researchers I want to add Ascorbic Acid (AA) to PHB in order to improve its biodegradability. AA is soluble in water but insoluble in those that are compatible with PHB (THF, Chloroform,...
08 October 2020 1,319 4 View
I have two questions: (1) I want to analyze the miscibility between two polymers: poly(lactic acid) PLA and poly(glycerol sebacate) PGSeb. However, I haven't found any information about the...
07 October 2020 269 3 View
How do I change insoluble recombinant proteins to soluble proteins? My recombinant protein is Aldose dehydrogenase from bacterial with around 35.0 kDa size. Now, My expression vector and...
06 October 2020 1,993 2 View
I am a beginner at autodock. Please, help me how to Mn metal atom parameters add to the autodock.
05 October 2020 7,630 5 View
Iron nitrate nonahydrate with PEG,PVP and ethane diol convert to iron oxides equation
04 October 2020 8,568 0 View
Hi, I synthesized the chitosan nanoparticles with encapsulated betaine but the quantity I obtained was much less than expected. I took 20mg betaine and dissolved it in 1ml ethanol because it is...
30 September 2020 8,324 3 View
I’m working with an API in a formulation with some polymers and surfactants that are highly soluble in deionized water. The solubility of the API should be pH dependent and thus it should be...
28 September 2020 8,701 7 View
The API (i.e. loteprednol etabonate )has poor solubility in water but has excellent solubility in Transcutol P which serves as cosurfactant in my microemulsion formulation. But when I added water...
25 September 2020 505 3 View
Is there any other way to calculate solubility of solute in solvent than MPAES?
25 September 2020 2,554 1 View
I am working on a compound development project which requires the addition of atypically high levels of inorganic stabilizers in an aliphatic polyketone resin. Melt processing evaluations of...
23 September 2020 5,974 1 View
How the high Tc superconductors divided into two separate levels depending on their doping mechanism that is electron and hole doped? How this doping happens in superconductors?
23 September 2020 3,849 5 View
I have synthesized a hexafluorophosphate salt of and Ir(III) cyclometalated complex. I have tried using a DEAE anion exchanger sephadex but that did not convert the PF6 to Cl. Is there another way...
23 September 2020 5,700 0 View
Surfactant aid in release of poor soluble drugs but in some cases discrimination is compromised. Can we use PEG if it gives better results in terms of release and discrimination power of...
22 September 2020 7,040 4 View
What is the solubility of ethinyl estradiol (EE2) in methanol? In the experiment, methanol was used to help dissolve, what is the reason for the flocs appearing after the storage solution is added...
21 September 2020 4,217 1 View
Drug is poorly water soluble and soluble in solvents like acetonitile , DMSO, mixture of methanol and water but they are toxic. kindly suggest any safe solvent.
19 September 2020 5,255 4 View
I have already install and load the package on Rstudio interface (R 3.5.3), but I cannot load the Database. I want to know how to use the package from loading Database to output results. Thanks...
18 September 2020 6,765 1 View