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Questions related from Michal Patarák
In the current pandemic situation, it is not possible to completely avoid a psychiatric patient carrying COVID-19 or being directly symptomatic. In addition, medical priority is to help anyone....
20 March 2020 4,733 10 View
According to ICD-10, schizophrenia has clearly established diagnostic criteria, including Schneider's first-order symptoms (Ertsranksymptome nach Schneider), such as thought insertion...
28 February 2020 6,869 4 View
Cannabidiol is an exogenous phytocannabinoid that has no psychoactive properties similar to Δ9-tetrahydrocannabinol. On the contrary, the antipsychotic and anxiolytic actions of cannabidiol have...
06 November 2018 5,812 2 View
The claustrum has remained one of the most enigmatic structures in the brain for several centuries. It is a thin, irregular sheet of gray matter, with one located on each side of the brain. It...
01 May 2018 501 4 View
Interest in the possibility that depression (from today's point of view especially anhedonia and so-called anhedonic depression) might reflect opioid deficiency, began in the early 1980s, when two...
05 March 2018 6,324 10 View
Aphanisis is a term introduced by freudian psychoanalyst Ernest Jones: it is the disappearance of sexual desire. According to Jones aphanisis is "the object, in both sexes, of a fear more...
17 February 2018 8,364 5 View
Benign hallucinations are usually non-threatening hallucinations in patients with Parkinson´s disease associated psychosis, in which the patient has a well-preserved sensorium and is aware of the...
15 February 2018 7,481 6 View
DSM-5 (2013) defines anhedonia in schizophrenia spectrum and other psychotic disorders as "the decreased ability to experience pleasure from positive stimuli or a degradation in the recollection...
13 February 2018 7,638 2 View
The attached article (1999) discusses the cases of four children between 5 and 17 years old, with congenital brain malformations involving total or near-total absence of cerebral cortex but who,...
14 January 2018 6,374 3 View
Anhedonia is defined as the inability to experience pleasure or a lack of pleasure from activities usually found pleasurable. Nevertheless what we are often calling as anhedonia, may be clinically...
14 January 2018 3,783 4 View
The work of Berridge and Kringelbach informs us that there are several hedonic hotspots in the brain, such as the hotspots in insula, orbitofrontal cortex, nucleus accumbens, ventral pallidum and...
14 January 2018 6,370 0 View
There are many psychotherapeutic schools and directions, whose therapeutic strengths lie mainly in the relationship between the therapist and the patient. So is it possible to say that what is...
28 November 2017 2,262 44 View
Caffeine is an antagonist of A2A adenosine receptors that are coupled to D2 receptors in striatally located heteromers. Antagonism on A2A has a similar effect as D2 agonism, so the dopaminergic...
13 November 2017 1,405 4 View
Sexual research shows that the sexual arousal of a male from a teenage girl is entirely normal. Is normal also hebephilia (persistent and dominant sexual interest by adults in pubescent children),...
08 November 2017 5,430 7 View
Dopamine system pathology in schizophrenia is predominantly presynaptic, and there are no significant changes in the number of postsynaptic dopamine receptors. However, according to Seeman and...
04 November 2017 4,718 5 View
Anhedonia is defined as lowered ability to experience physical or social pleasure. It is a core symptom of major depression and it is often part of negative symptoms in schizophrenia. Why is this...
31 October 2017 4,316 15 View
During the psychosis irrespective of particular diagnosis the dopamine synthesis capacity is increased...
30 October 2017 9,109 9 View
SHAPS is a self-assessment scale, simple to test and complete, with 14 questions, focusing on four domains of hedonic experience: interests and entertainment, social interactions, sensual...
30 October 2017 6,441 0 View
I would like to ask if a difference between the BSIT tests (BSIT, BSIT-A and BSIT-B) in the particular odours used also affects the assessment of olfactory functions? Is it preserved - despite...
12 October 2017 9,674 0 View
Why do many articles and even chapters in textbooks constantly mention that dopamine release in the mesolimbic system (the so-called reward system) correlates with euphoria and mediates hedonic...
06 October 2017 6,750 2 View
Psychosis associated with Parkinson's disease is a very heterogeneous clinical unit. Is there any inherent link between visual hallucinations in the case of dementia in Parkinson's disease (which...
27 September 2017 6,600 4 View
Serotonergic and noradrenergic neurons might act as surrogates for the dopaminergic system, by taking up exogenous levodopa and converting it to dopamine and then releasing it, at the expense of...
25 September 2017 707 5 View
The concept of antipsychotic equivalence has been used for decades to compare the dosages and efficacy of antipsychotics, even though it is highly debatable, and with the widespread of atypical...
19 September 2017 6,247 7 View
Agomelatine is a melatonin (MT1/MT2) receptor agonist and a serotonin 5HT2C antagonist (increasing dopamine and norepinephrine in the frontal cortex). It is an antidepressant and it can also...
18 November 2016 8,307 3 View
Experience with off label deep brain stimulation in psychiatry.
02 November 2016 3,492 7 View
Internet gaming disorder is just one type of problematic use of the Internet, although it has its own specific characteristics of course (though merging with an "offline gaming disorder" which is...
01 January 1970 1,705 6 View
The drug vinpocetine is currently being promoted in Slovakia by certain pharmaceutical company for use in psychiatry. Vinpocetine has a rich history and is mainly used to improve cognitive...
01 January 1970 5,415 3 View
Agomelatine is a melatonin receptor agonist (MT1 and MT2 receptors) and serotonin 5-HT2C and 5-HT2B receptor antagonist, which theoretically resynchronizes circadian rhytms of man affecting MT1,...
01 January 1970 4,309 0 View
Is not the concept of drive (the original german term "Trieb" is also translated as "instinct") merely a scientific metaphor, a construct? Is this term for a scientific discourse still useful?...
01 January 1970 838 17 View
The Praecox-feeling is experiencing a resurgence in psychiatry, or - better to say - a conceptual reconstruction. Several authors (the first of all was Henricus Copernicus Rümke in 1941) claim...
01 January 1970 1,515 2 View
