Agomelatine is a melatonin (MT1/MT2) receptor agonist and a serotonin 5HT2C antagonist (increasing dopamine and norepinephrine in the frontal cortex). It is an antidepressant and it can also reduce anxiety and re-synchronize circadian rhythms. De Berardis et al (2012, Ann Clin Psychiatry) informed about a female patient with PTSD with substantial improvement after agomelatine treatment. In my clinical practice, I have successfully used agomelatine in the treatment of female patient with PTSD and comorbidity with a psychotic disorder. It is therefore possible that anxiolytic (and many other) properties of agomelatine can help to alleviate symptoms of PTSD.  

Article Agomelatine for the Treatment of Posttraumatic Stress Disord...