Does anyone have information about Zeise's salt (please see attached note) as a starting point for developing new chemotherapy drugs?
Dear Anthony,
What you have mentioned is already under investigation. The chemotherapy of cancer may get a boost in the forthcoming years. .Zeise’s salt is being researched at the Innsbruck university (Austria) for possible anti-cancer agent as does its potent analog molecule cisplatin, a potent chemotherapy drug cisplatin.
Zeise’s salt could be a cancer fighter
A new family of chlorinated substances has shown potential for enhancing the chemical battle against cancer.
The chemotherapy of cancer may get a boost in the forthcoming years. A nearly 200 years known molecule called Zeisse’ salt is being researched at the Innsbruck university (Austria) for possible cancer fighting capacities. The molecule contains three chlorine atoms and the Austrian team thinks Zeisse’s salt, or with its full name potassium trichloroplatinate, could be a starting point for new chemotherapy medicines. “ This study also shows that one does not always need to design elaborate new molecules or seek out unusual natural products”, the researchers comment, “sometimes old molecules can be hidden jewels to follow up on.
Zeisse’s salt also contains a central atom of platinum, as does its potent analog molecule cisplatin, a potent chemotherapy drug cisplatin.
http://www.chlorinethings.eu/home/blog/improving-stuff-with-chlorine-chemistry/your-health/zeise-s-salt-could-be-a-cancer-fighter
http://cen.acs.org/articles/93/i6/Zeises-Salt-Cancer-Fighter.html?type=paidArticleContent
Hoping this will contribute to the discussion on this important agent.
Rafik
Dear Rafik,
Thank you for your rapid reply and the interesting information. I do not have access to the Angew.Chem. Int. Ed. article; any chance you might be able to send me a copy?
Thank you again, and good luck in your research.
Tony
Dear Rafik,
Thank you for the copy of the paper! Very interesting and informative. Best wishes, Tony.
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