When digested, AI milk releases beta-casomorphin7 (BCM7), an opioid with a structure similar to that of morphine that some studies have linked with autism. Does anyone have information on the mechanism of BCM7 formation?
Hello... Anthony Foris
In vitro studies have shown that, the bioactive peptide β-casomorphin-7 (BCM‐7) is produced by the successive gastrointestinal proteolytic digestion of β-casein A1, but such cases were not seen in β-casein A2 type milk.
Kindly see these two articles:
Article Enzymatic release of neocasomorphin and β-casomorphin from b...
Article Release of β-casomorphins 5 and 7 during simulated gastro-in...
Pictorial representation made by me is also in attachment.
Dear Laxmana Naik,
Thank you for the information on the mechanism of release of BCM-7, and the very nice pictorial representation. Best of luck in your research. AF
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