It's probably a HILIC column with an ELSD detector. Most carbohydrates like Erythritol and sugar alcohols like Glycerol are water soluble. But it really depends on your sample matrix and your expected concentrations.

Thank you.

The samples are under 0.2% of concentration of each component and they are water soluble.

What is your sample matrix?

Viviana,

if you don't have ELSD you can use refractive index detector as well.

regards,

G

Thank you.