Will I need dose calculation sustained release buccal drug delivery?

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Namdeo Shinde

Dear Jayesh, i am not getting your question so please elaborate it that means what you actually want?

Jayesh Wavhale

actually am working with buccal mucoadhesive tablet and drug half life is 3 hrs but am sustaining for 12 hrs so will it need dose calculation or can i give the same dose as oral for 12 hrs?

Ahmad Mohamad Zaiter

Sorry ur question isn't clear at all ! ......

U want to calculate in vitro release of sustain release formulation ?

Or u r asking about is the half life of drug will be different for sustain release ?

Please clarify ur question, paraphrase it !