Another problem that we will have to face is that regardless of the country, people in difficult financial conditions will most likely be left out of several vaccination campaigns.

Unfortunately, inner misery preys on the vulnerable citizens. 😢😓

I don't think it has a negative side effect regarding some groups of people because if so, UK would say that !! 🌹❤

Thanks a lot Dr. Diana A. Ali really thanks

Dear Dr. Kanaan!

You spotted an essential point. The objective is that everyone of us could have an effective, suitable vaccine:

1) Heidi Ledford (2020). Oxford COVID-vaccine paper highlights lingering unknowns about results -The Oxford–AstraZeneca partnership is the first major developer to publish detailed data from phase III trials. News Nature 588, 378-379 (2020) Open Access:

https://www.nature.com/articles/d41586-020-03504-w

2) Andrea D. Branch (2020). How to Survive COVID‐19 Even If the Vaccine Fails Hepatology Communications Volume 4, Issue 12, December 2020, Open Access:

Article How to Survive COVID‐19 Even If the Vaccine Fails

3) Nilesh Kumar Sharma et al. (2020). Is a COVID-19 vaccine developed by nature already at work? Medical Hypotheses Volume 145, December 2020, Open Access:

Article Is a COVID-19 vaccine developed by nature already at work?

4) Editorial (2020). COVID-19 vaccines: no time for complacency The Lancet, Nov. 21, 2020, Open Access:

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32472-7/fulltext

Hoping for the best, preparing for the worst. Yours sincerely, Bulcsu Szekely

Thanks a lot Dr. Bulcsu Szekely really thanks.

While different groups are working on protocols to make vaccines workable for all ages and vulnerable groups, we do know that any vaccine which is rolled out in the coming months may not work for everyone. Current predictions suggest that there may be hundreds of thousands who may not benefit from a COVID-19 vaccine roll out as of right now and will probably be made to wait longer. Some groups may also have to wait a little longer to have a vaccine ready for their needs. Again, different vaccines can also contain different components, which may affect people differently. Adenovirus vaccines, for one, which has been made use of by at least 4 different COVID-19 vaccine makers can have altered, sometimes severe side-effects for those with compromised immunity, lung function, or heart disease.

https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/coronavirus-vaccine-are-there-people-who-cannot-get-vaccinated/photostory/79385457.cms?picid=79385530

It may be create effect on people according to their food habits & environment. I hopefully positive side.

Thanks a lot Dr. Paramasivam Sivaraj really thanks

Dear Dr Manal Hadi Kanaan, I appreciate for asking this question. Though the virus mutates, every one will be vaccinated, the side effects, if any, will be known only later. I assume that there won't be any significant side effect. Hope all get covered under vaccination program. Warm regards Yoganandan G

Thanks a lot Dr. Yoganandan G. really thanks

Dear Dr. Manal thank you for the beautiful question ;

1- Pfizer didn't authorize the use of vaccine in those below 16 years old

2- No enough study for the use during pregnancy

3- No enough study for the use during lactation

4- immune suppressed patients or HIV patients can use the vaccine

Thanks a lot Dr. Laith G. Shareef really thanks

Of course vaccine not suitable for all groups, and exception includes pregnancy, Lactation, allergic person and children below 16 years.

Thanks a lot Dr. Abdulhadi Mohamed Jumaa really thanks

Probably not, it is like all medicines, about ones predisposition, side effects and effectiveness to protect from this disease, but are these vaccines tested thoroughly enough?

Thanks a lot Dr. Ken Drinkwater really thanks

In addition to that all those with history of allergy are contrindicated

An issue that should be discussed is the negacionism. Several people are misguided by fake news.

There are people who vaccinated their family members but advocate against mass vaccination. Why? Possible reasons:

Greed: They want the money invested elsewhere;

Ignorance;

Cruelty; and

All the above issues.

Some people in my country are against vaccination but favor extremely toxic pesticides. This is genocide.

Thanks a lot Dr. Abdulhadi Mohamed Jumaa really thanks

Thanks a lot Dr. A. P. Araújo really thanks

Another problem that we will have to face is that regardless of the country, people in difficult financial conditions will most likely be left out of several vaccination campaigns.

Unfortunately, inner misery preys on the vulnerable citizens. 😢😓

Persons under 18 years of age, pregnant women, the infection Covidien 19 will not be vaccinated within the last 6 months spent in Turkey

Everyone will be vaccinated, especially healthcare workers, over the age of 65 and those with comorbidities.

please see the below RG link

Who Needs The COVID-19 Vaccine?

Thanks a lot Dr. Nikolaos Andreopoulos really thanks

Thanks a lot Dr. Serdar Kalemci really thanks

The Centers for Disease Control and Prevention (CDC)Trusted Source recommend a range of vaccinations for Americans of all ages. These vaccines help prevent dangerous diseases that in the past would sicken countless people each year.

However, these vaccines may not be right for everyone. The CDC advises that certain people not get specific vaccines, or to wait before getting vaccinated. This is because different vaccines contain different components, and each vaccine can affect you differently. Your age, health conditions, and other factors all combine to determine if you should get each vaccine.

https://www.healthline.com/health/vaccinations/immunization-complications#overview

Despite the fact that vaccines are proven to save lives, some people still don't get the vaccines that are freely available to them, both in the UK and beyond. This puts them, their children, their family, and their community at risk of infectious diseases. To some degree, this is thought to be due to vaccines being a victim of their own success. Some countries now rarely see the deadly diseases which vaccines prevent and so people may become more frightened of perceived harm from a vaccine than the risk of the disease itself. But concern about safety is only one reason why people don't take up vaccines. Recent research papers and reports offer some useful insights into vaccine hesitancy.

https://www.meningitis.org/blogs/mrf-view-on-anti-vaccination

Thanks a lot Dr. Sura Saad really thanks

Dear Manal Hadi Kanaan There are reports that people's immune systems respond to vaccines differently. There are anumber of factors that will determmine the outcome:

https://www.weforum.org/agenda/2020/09/5-ways-immune-responses-covid-vaccines-coronavirus-health-pandemic/

Regards!

Thanks a lot Dr. Arbind K. Choudhary really thanks

To every vaccine a portion of population did not develop immune response. Same may b case with COVID 19.

Dear Manal Hadi Kanaan Current predictions suggest that there may be hundreds of thousands who may not benefit from a COVID-19 vaccine roll out as of right now and will probably be made to wait longer.Some groups may also have to wait a little longer to have a vaccine ready for their needs. I agree with the link which formed the basis of discussion:

https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/coronavirus-vaccine-are-there-people-who-cannot-get-vaccinated/photostory/79385457.cms

Regards!

Thanks a lot Dr. Arbind K. Choudhary really thanks. Also, I fully agree with this link. My sincere gratitude, Doctor.

We hope it works for all!

Thanks a lot Dr. Mubashir Ali Rather really thanks

Thanks a lot Dr. Hassan Izzeddin Sarsak really thanks

While vaccination is a crucial preventable act which safeguards communities from the fear of infectious diseases, there are some people who are not suited for vaccination. People who are advised to wait out, or avoid vaccination may have underlying factors which may deter vaccines to work on them. Age, health conditions may also play an important role. Reports of growing vaccine hesitancy, which may again, add to our concerns. https://m.timesofindia.com/life-style/health-fitness/health-news/coronavirus-vaccine-are-there-people-who-cannot-get-vaccinated/photostory/79385457.cms?picid=79385530

While different groups are working on protocols to make vaccines workable for all ages and vulnerable groups, we do know that any vaccine which is rolled out in the coming months may not work for everyone. Current predictions suggest that there may be hundreds of thousands who may not benefit from a COVID-19 vaccine roll out as of right now and will probably be made to wait longer. https://m.timesofindia.com/life-style/health-fitness/health-news/coronavirus-vaccine-are-there-people-who-cannot-get-vaccinated/photostory/79385457.cms?picid=79385530

No vaccine is side-effect free. There will always be chances of people developing side-effects. The risk weighs more for those who have experienced troubles with past vaccine doses. People who have specific allergies, or have suffered from threatening complications may be advised to wait out before they get a jab of an experimental COVID-19 jab. Since this is the first time a vaccine for COVID-19 is being developed, the odds of side-effects will be higher than ever. https://m.timesofindia.com/life-style/health-fitness/health-news/coronavirus-vaccine-are-there-people-who-cannot-get-vaccinated/photostory/79385457.cms?picid=79385530

Kindly check https://api.nationalgeographic.com/distribution/public/amp/science/2020/08/how-coronavirus-covid-vaccine-mandate-would-actually-work-cvd

Thanks a lot Dr. Chinaza Godswill Awuchi really thanks

The vaccine is still not available in market. No complaint during trial period. Pfizer has announced the children will not vaccinated below age of 16 years.

Thanks a lot Dr. Aijaz Panhwar really thanks

Thanks a lot Dr. Terri Purvis

People with severe allergy or history of anaphylactic reaction to previous vaccination are, potentially at risk of developing severe reaction to the vaccine.

Thanks a lot Dr. Salman Ajlan really thanks

Thanks a lot Dr. Terri Purvis

I think no vaccine clinical trials have so far included pregnant or lactating women, nor even women who are planning to get pregnant, some trials are expected to begin in January.

Thanks a lot Dr. Mahammad Khuddush really thanks

Like any vaccine, it requires an individual approach. Use caution in the flesh until canceled. These are people with allergies, children under 3 years of age, as well as elderly people over 65. Also infected with HIV, and patients with autoimmune diseases.

Regards, Sergey

Thanks a lot Dr. Pushkin Sergey Viktorovich really thanks

I think first testing should be done with young and healthy peoples elders pregnant women and children should be vaccinated after got sucess

Thanks a lot Dr. M.K. Tripathi really thanks

It's a biggest chellenge for whole world..many people can't afford vaccines. And it's chellenge for government to vaccinate whole population.

Thanks a lot Dr. Amjad Ali really thanks

We were told people with serious alleges not to take it. Otherwise should be OK.

Thanks a lot Dr. Michael Issigonis really thanks

Vacicene means that must we work for everyone ....if not working then ....we have to think madam...

Yes, not all. I cannot get vaccinated.

I'm allergic. (the so-called Quincke's edema).

Therefore, the vaccine must undergo rigorous tests and research.

https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/coronavirus-vaccine-are-there-people-who-cannot-get-vaccinated/photostory/79385457.cms

Thanks a lot Dr. M.K. Tripathi really thanks

Thanks a lot Dr. Terekh Alexandr M. really thanks

Thanks a lot Dr. Anwar A. Abdulla really thanks

WE hope that these vaccines works for everyone with no side effect so that people can return back to their normal life as before

الكثير لايثقون باللقاح

Thanks a lot Dr. Lamia Al-Naama really thanks

Thanks a lot Dr. Zamiel Salih really thanks

It's important to know that even after a vaccine is approved, it's still monitored for safety. It's noteworthy to state that every vaccine has potential for side effects. From the body of knowledge, not everyone could be vaccinated. Previously, we have had various short and long terms adverse, sometimes fatal effects following vaccination which may range from allergies to non-communicable diseases such as development of T2DM. Therefore, except if to be the first time, Covid-19 vaccine may not be exempted of its own downsides. We pray it's minimal. What am not sure if the current mutant strains would not have significant impact on the vaccine. We hope that different vaccine types would limit any foreseeable effects from this angle.

Some adverse effects reported so far in similar vaccines

https://www.cdc.gov/vaccines/vac-gen/side-effects.htm

Thanks a lot Dr. Kamoru A. Adedokun really thanks

Like some vaccines, COVID-19 can cause malfunctions or negative reactions in the body. Therefore, some people cannot get the vaccine. In addition, the protocol of delay and experimentation in the development of vaccines seems, in my opinion, not to be respected. This will create suspicion in people who are against any form of vaccination.

Good questions that the countries producing the vaccine have yet to answer, especially with the emergence of new strains of the virus

Thanks a lot Dr. Ben Boubakary really thanks.

Thanks a lot Dr. Aqeel yousif Alshukri really thanks.

There's a lot of curiosity surrounding the development of a suitable COVID-19 vaccine. With casualties breaching the 55 million mark, it is paramount that we get our hands on a novel coronavirus vaccine as soon as possible. More than 45 candidates, of which, 7 are already in critical stages of roll-out are being looked at as the most promising candidates...

Thanks a lot Dr. Sandip Kumar Gupta really thanks.

There are always people that can't get vaccinated. It could be because they are immunocompromised, too young, or allergic.

Thanks a lot Dr. Chuck A Arize really thanks.

There could be future issues as some defects were observed in some people vaccinated.

Thanks a lot Dr. Ajibola Ibrahim Quadri really thanks.

Dear Manal Hadi Kanaan this is certainly an important question. Please see this useful recent article entitled

"Who Can and Can’t Safely Get the COVID-19 Vaccine"

https://www.healthline.com/health-news/who-can-and-cant-safely-get-the-covid-19-vaccine

It is pointed out in this article that "Experts say the COVID-19 vaccine is safe for most people" but "people who’ve had severe allergic reactions to any ingredients in the vaccine should not get it."

Dear Dr. Frank T. Edelmann Thank you very much, Doctor. In fact, very useful information about who can safely take the vaccine and who cannot, especially since we previously read about those who are not allowed to take the vaccine and they are pregnant and breastfeeding and people with autoimmune diseases, but here we find another group that cannot take the vaccine, they are the ones who develop allergic reactions to the vaccine or any of its ingredients by which if a person has a severe allergic reaction to the first shot of the COVID-19 vaccine, the CDC advises them not to get the second shot. Truthfully, very useful information always supports us with everything valuable, useful, and new. My sincere gratitude, Doctor

A vaccine against Covid-19 may not work well in older people who are most at risk of becoming seriously ill and dying from the disease, say, scientists, which may mean immunizing others around them, such as children.

Prof Peter Openshaw, from Imperial, one of the members of the UK’s Sage scientific advisory sub-group Nervtag, told the House of Lords Science and technology committee it was this week considering a paper on targeting different groups in the population with vaccines.

“Sometimes it is possible to protect a vulnerable group by targeting another group and this, for example, is being done with influenza,” he said. “In the past few years, the UK has been at the forefront of rolling out the live attenuated vaccine for children.”

Giving the nasal spray flu vaccine to children who do not often get severe flu protects their grandparents, he said. Immunizing health and care workers – who are likely to be the first to get the vaccine – would also help protect older people who have the most contact with them

Who cannot get vaccinated?

There's a lot of curiosity surrounding the development of a suitable COVID-19 vaccine. With casualties breaching the 55 million mark, it is paramount that we get our hands on a novel coronavirus vaccine as soon as possible. More than 45 candidates, of which, 7 are already in critical stages of roll-out are being looked at as the most promising candidates.

Having a vaccine ready, which may be first administered to high-risk groups first will grant us immunity and stop the spread of the viral outbreak across the world. It may also give us hope that someday, we will be able to resume life in a normal manner. But, there's a chance that these contenders may not suit everyone, despite best efforts. We have to bear in mind that there are also people who cannot be, or not advised to go through the vaccination process

While vaccination is a crucial preventable act that safeguards communities from the fear of infectious diseases, there are some people who are not suited for vaccination. People who are advised to wait out, or avoid vaccination may have underlying factors that may deter vaccines to work on them. Age, health conditions may also play an important role. Reports of growing vaccine hesitancy, which may again, add to our concerns.

Complications and fears of immunization

While different groups are working on protocols to make vaccines workable for all ages and vulnerable groups, we do know that any vaccine which is rolled out in the coming months may not work for everyone. Current predictions suggest that there may be hundreds of thousands who may not benefit from a COVID-19 vaccine roll out as of right now and will probably be made to wait longer.

Some groups may also have to wait a little longer to have a vaccine ready for their needs. Again, different vaccines can also contain different components, which may affect people differently. Adenovirus vaccines, for one, which has been made use of by at least 4 different COVID-19 vaccine makers can have altered, sometimes severe side-effects for those with compromised immunity, lung function, or heart disease.

We tell you some of the other risk factors which may dissuade vaccine development and inoculation in the coming months:

Those who have developed allergies to previous vaccines

No vaccine is side-effect free. There will always be chances of people developing side-effects. The risk weighs more for those who have experienced troubles with past vaccine doses. People who have specific allergies, or have suffered from threatening complications may be advised to wait out before they get a jab of an experimental COVID-19 jab. Since this is the first time a vaccine for COVID-19 is being developed, the odds of side-effects will be higher than ever.

People who have seriously compromised immunity

A vaccine works to protect the ones who have frail immunity or belong to a high-risk category. However, people who have seriously compromised immunity, suffering from chronic complications that could have impacted their immune functioning may not deliver a strong response. There are also people with existing health conditions or problems that make them have a non-functional immune system, such as the ones who might be taking immuno-suppressant drugs. Vaccines for them may not suit them well either. Hence, caution is strongly advised.

Are under 14 years of age

Infants and toddlers can act as super-spreaders of COVID-19 and in rare cases, may even suffer from lingering life-threatening complications due to COVID-19. Making a vaccine for them is also crucial to reopening schools and recreation centers safely. However, certain vaccine doses may be unsuited for growing children's immune systems. Children's immune systems may also react differently to a vaccine, as compared to others, which is also a reason why not many vaccine trials cover children. Right now, it may be possible that children may have to wait a little longer when a COVID-19 does get approved for use.

Pregnant women

Pregnant women, much like children are not really made part of a COVID-19 vaccine trial, and never has there been a vaccine specifically designed for expecting women during such viral outbreaks.

Experts believe that the experimental doses used in COVID-19 vaccines may be unsuitable for a growing baby's health, and may make a pregnant woman showcase adverse side-effects. Hence, they will also have to wait a while or follow discretion when it comes to getting vaccinated in the future months. However, the delay will have consequential impacts on women who are pregnant in times of COVID. Hence, corrective steps need to be taken at the earliest to protect the vulnerable group.

Dear Manal Hadi Kanaan here is the link from which the last answer was copied and pasted without citing the source:

Coronavirus vaccine: Are there people who cannot get vaccinated?

https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/coronavirus-vaccine-are-there-people-who-cannot-get-vaccinated/photostory/79385457.cms

Dear Dr. Frank T. Edelmann Thank you very much, Doctor. Yes, I noticed that too. My sincere gratitude, Doctor.

Thanks a lot Dr. Getasew Amogne Aynalem really thanks.

It should work for most people. However, there are some people who think the vaccine is promoted to make some people rich, so they say they are not interested to get it.

It is not preferable to give the vaccine to pregnant women and children. And the vaccine may cause an immune response and may fail to do so.

Hopefully, the vaccines will help different age groups. Let's be positive and grateful to the Almighty.

Dear Manal Hadi Kanaan and all readers of this thread: Please see this very recent and instructive link entitled

Covid variants: latest on the South African, UK and Brazilian variants

https://www.bhf.org.uk/informationsupport/heart-matters-magazine/news/coronavirus-and-your-health/covid-variant

The article provides a good overview about the effectivity of different vaccines against the various coronavirus variants.

Very few things work for everyone and there will always be people that can't get vaccinated. It could be because of allergic reactions or a compromised immune system.

Dear @Manal Hadi Kanaan I think the vaccine is likely to work for everyone. Where there is no free vaccination or people are highly illiterate and conservative, there is possibility that some people may be left out.

Regards!

Dear Manal Hadi Kanaan in this context please also see this very recent (February 10, 2021) article entitled

5 factors that could dictate the success or failure of the COVID-19 vaccine rollout

https://theconversation.com/5-factors-that-could-dictate-the-success-or-failure-of-the-covid-19-vaccine-rollout-152856

Thanks a lot Dr. Michael Issigonis really thanks.

Thanks a lot Dr. Isam Alkhalifawi really thanks.

Thanks a lot Dr. Zane Asher Green really thanks.

Thanks a lot Dr. Chuck A Arize really thanks.

Dear Dr. Arbind K. Choudhary Thank you very much, Doctor. In fact, many of those around us do not want to take the vaccine if it is available. I think they feel unsure about the side effects that they hear about and that are transmitted by the media sometimes. My sincere gratitude doctor.

The vaccine (any type of vaccine) does not work for everyone.

In fact, a (more or less wide) "risk" band remains open.

Regarding the "return to normal", it is clear that there will be no going back.