Hi everyone,
This is just a 'out-of-curiosity' question, but why is the cerebellum used as the reference point? What is the reasoning? I was always told is it because it is 'silent' compared to the cortical regions, but obviously the cerebellum is also active. Is there any paper that explains the choice, or if a better reference region or method is available?
Thank you!
Im not sure but probbably because of its volum and location. Those specifics in mouse's brain may be are important for the methood.
Dear Haram,
I have been always heavily involved in this past discussions when we measured with telemetry EEG. The answer has been always that the cerebellum is obviously active but the neurons fires at very high frequencies whereas the most interesting frequencies for a "normal" EEG are much lower (0.5-100 Hz). That is why most likely the cerebellum is taken as reference and additionally if you have differential electrodes you get greater signal/noise ratios. Hope this helps.