Is there any reason for it not growing back? Is a gene responsible?
However in some other parts of the body it is dense and difficult to remove, in contrast it is likely very easy to lose hair?
The most common reason why the hair never grows back is that hair follicle stem cells (HFSCs) exhaust. Niche is also important to maintain the number of HFSCs. HFSCs is localized to budge area. Several papers have reported that oncogenic stress such as c-Myc activation leads to the transient proliferation and consequent loss of HFSCs.
It's important to keep in mind that there are 100 reasons to lose hair. Some are not due to defective genes. Some are due to one gene. Some are due to dozens of genes. Some are due to destruction of stem cells; other hair loss conditions do not affect stem cells.
Genetic hair loss and alopecia areata are two hair loss conditions with the closely genetic link. A few scarring alopecia (such as CCCA) may have a genetic link. Hair loss from crash dieting has not genetic link that we know of and does not deplete stem cells.
Hair loss is a broad field and one must clearly define the condition they are studying in order to develop appropriate models.
Absolutely- finasterise and minoxidil are FDA approved. PRP and laser are off label considerations. Of course hair transplantation surgery remains a good option.
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