Why does uninephrectomy in mice lead to hypertension?

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Ebenezer Idowu Ajayi

Uninephrectomy causes salt-sensitive hypertension even when on a normal-sodium diet, which is mineralocorticoid receptor-dependent. This can also lead to glomerular damage.

Ali A R Aldallal

Strain differences in the development of hypertension and glomerular lesions induced by deoxycorticosterone acetate salt in mice

Article Strain differences in the development of hypertension and gl...

Josef Evers

The usual mechanism of hypertension after uninephrectomy is glomerular damage by overload of the glomeruli of the remaining single kidney.