Why does the presence of different contamination change the pH of media in different ways?
Different type of contamination like fungal make different types of metabolite which mostly acidic of slightly acidic. but if they can't tolerate that concentration of metabolite cells are going to dye due to cell lysis, thats why pH rises.
As we know so far, around 25 proteins and peptides are known to involve in amyloid disease. If we assume that the fibrillation is an intrinsic feature of all polypeptides, and that we have tens...
31 December 2018 3,146 3 View
In an assay if we find that the best pH for a protein which will be injected to the patients, is around 3, it is ok that during formulation, we use an acidic buffer.In similar situation if we...
04 May 2018 2,656 2 View
06 July 2015 3,288 6 View
Is it Ok to Analysis of the significantly / meaningfully of an inhibitory effect with anova-test or t-student?We work on a compound which can decrease the cytotoxicity effect of another compound...
11 December 2014 9,777 3 View
We are working with a protein to induce fibrillation forms. Our FTIR (deep peak at 1624 qnd 1695) results and AFM images (twisted long fiberils) confirmed fibril formation. In spite of these...
08 September 2014 2,563 10 View
06 July 2014 9,137 3 View
In many proteins such as lysozyme and alpha-synuclein, only a limited part of protein participate in cross-beta sheet and fibril formation. In alpha synuclein from 140 residues only about 60...
01 February 2014 1,356 0 View
How to calculate the RMSD values for a MD simulation using MOE?
07 August 2021 0 0 View
When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.
16 June 2021 0 0 View
Hi, I want to start testing pitfall trap to obtain ants samples, but I need to conduct molecular analysis on those insects. So, what kind of fluid can I use? Ethanol expires too early and I need...
03 March 2021 5,978 5 View
02 March 2021 3,060 3 View
Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...
02 March 2021 4,569 4 View
Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...
02 March 2021 3,024 2 View