Why does cytochrome remove the effect or modulate drugs by oxidation of free radicals that also have effects? glotathione then performs an antioxidant process by reducing drugs
ACTION glotathione is an act of complementarity to or an opponent of the cytokrome.
Does the drug revert to its normal non-oxidized state by glotathione?
And ultimately how drugs are eliminated within these two opposing mechanismshy does cytochrome remove the effect or modulate drugs by oxidation of free radicals that also have effects?
Oxidation proceeds by a free-radical chain mechanism and includes a rare radical–radical combination step in the propagation part. The radical–radical combination step doesn’t terminate the chain in this reaction because O2 is a 1,2-diradical. Cytochrome is an oxidant, glutathione is an antioxidant with more than 90% of the total glutathione pool in the reduced form. Depending on their ration they can act in opposing ways. The drug has its own chemistry and is hard to predict if an oxidized drug reverts to the reduced form. Many times there is a subsequent transformation of the oxidized drug intermediate to form a metabolite that can be eliminated.
Personally, I did not understand your question. Each sentence is puzzling. This is an example: "modulate drugs by oxidation of free radicals that also have effects" In addition, always check spelling, which is so easy to do. Be professional.
CP450 does not produce free radicals. Glutathione peroxidase does not scavenge free radicals. Glutathione reductase catalyzes the reduction of disulfide (GSSG) to form glutathione (GSH)
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