It is important that the degradation rate of the scaffold is equal to the rate of tissue regeneration. In addition, the mechanical properties must be preserved during biodegradation so that the scaffold allows cell proliferation and transport of nutrients while the generation occurs.
Hello, agree with Carlos. Can you please give some elements about your interest. Regarding type of tissue/scaffold, you can have numerous key factors
KR, Nabyl
Hi, if without a good degradation properties on the scaffold, cell proliferation might be affected as most of the scaffold not only provide a bed for cell proliferation but also it provides necessary nutrient for the cell growing step.
It's very crucial because the scaffold is a temporary supportive template that should degrade over time. So the degradation rate of the polymer should match the rate of tissue regeneration. The polymer should have good initial mechanical properties that will decrease or decline in the course of degradation. Degradation products should be non-toxic. The degradation rates, mechanisms, and products are very important factors
If your application is implant in body must you study degradation rate with properties and discuss the mechanical properties of implant tissue with degradation also its necessary to know bio compatible for any implant tissue in body
It is very important to be aware of scaffold degradation behaviour in the body, we can incorporate growth factors or drugs within the scaffold matrix, required for the regeneration of specific tissue/cells that will be released from the scaffold when it will degrade in the physiological environment. Thus, enhancing the overall regeneration process.
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