Hi,

I heard about the use of IC50 to test the susceptibility of a bacterial strain to a given drug. I didn' t understand very well why people use it to test the acceptor strain before performing transformation experiments,.Would it not better to perform a minimal inhibitory concentration (MIC) instead? Why do you need to know the half minimal inhibitory concentration of your acceptor strain? Maybe it makes more sense to know the concentration of the drug that completely inhibits the drug doing a MIC...Sorry,  It is completely new  for me, so maybe I can't to understand this fully. Do you have an idea?

Thank you very much