dear colleague

Which review do you mean?

First, concerning the 25OH vit D threshold. If you are conservative and accept only RCT prove, than the AIOM guideline is your guide, stating at least about 50 nmol/l for maintaining healthy bones.

However if you include the growing evidence of a much broader activity field for vit D, starting with healthy muscles, a healthy immuun respons, etc, than you should follow the international experts stating that about 75 nmol/L is the minimum.

Second, regarding calcium, a low calcium results in an increased demand for 1,25(OH)2 vit D having a short halftime and thus decreasing your vit D status. In other words, a low calcium intake is a confounder in vit D deficiency.

Everyone knows that calcium is needed for strong bones – which are particularly important for participants of high impact sports – but calcium has lots of other, lesser-known health benefits.

For example, according to the EFSA, Calcium contributes to normal neurotransmission. Neurotransmission – the sharing of messages between brain cells – has a role in the way we learn, behave, move and feel.

Calcium contributes to normal muscle function and helps certain enzymes in your body function normally, which digest the food you eat and absorb other important minerals and vitamins you need.

This essential mineral also contributes to normal metabolism, which in turn impacts your energy levels – you can’t excel in your chosen sport if you’re feeling lethargic.

Please check

Kovacs CS. Calcium and Phosphate Metabolism and Related Disorders During Pregnancy and Lactation. 2018 Dec 4. In: Feingold KR, Anawalt B, Boyce A, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279173/

Dear friends calcium is number 1 in all elements ,but many dont know its

ndeed, an attractive hypothesis for the mechanism underlying cardiac muscle dysfunction during heart failure, the leading cause of mortality in the developed world, is that impaired calcium release causes decreased muscle contraction (systolic dysfunction) and defective calcium removal hampers relaxation (diastolic dysfunction). Given that the measurement of cellular calcium is relatively straightforward, the obvious experiment required to address this important issue is to measure calcium in heart muscle cells from failing hearts. Such measurements have been done in isolated cardiomyocytes and, though there is a fair amount of variability in the published reports, the data tend to support the concept of a decrease in SR calcium release and a defect in the termination of release. These results imply that there are presumably defects in SR calcium release in vivo. However, there are no data showing that calcium levels are chronically elevated in heart muscle in failing hearts. Such studies await the development of reliable techniques using calcium indicators with adequate signal to noise ratios and detection systems that will permit measurements of intracellular calcium in the living heart in intact organisms.so we need water to contain calcium ,so drinking RO water is dangerous,

if i answer one reply i need to put 10 replies ,because calcium is very very important ,but vitamin D is required too,

o account for 30% of all deaths [1]. Thus, identifying modifiable risk factors and treatments remains a high priority for CVD prevention. Vitamin D deficiency, primarily known for its role in bone and mineral regulation, has garnered interest for its potential role in many other disease processes, including CVD. There is strong evidence from observational studies that have linked low serum levels of 25-hydroxyvitamin D [25(OH)D] with poor cardiovascular outcomes [2]. Vitamin D is an attractive interventional target, as serum 25(OH)D levels are modifiable and treatment is relatively inexpensive. Furthermore, as it is estimated that approximately one billion people in the world have either deficient or insufficient levels of 25(OH)D, vitamin D intervention can potentially impact a large population [3].

Despite encouraging results from observational epidemiological studies, randomized controlled trials (RCTs) of vitamin D supplements have yielded mixed results regarding cardiovascular outcomes [4-8]. However, to date, no large-scale trial of vitamin D supplements with CVD as a primary outcome has been completed [9]. While several large-scale RCTs are currently underway, the lack of persuasive evidence has resulted in differing guidelines and practices regarding the definition of vitamin D deficiency, populations to be screened, and the ideal level of supplementation.

Because vitamin D promotes the intestinal absorption of calcium, vitamin D is often prescribed in conjunction with calcium supplementation, particularly in populations at risk for bone loss, such as post-menopausal women and older adults [10].

Again i shall say that calcium is needed ,but sources of calcium are important

1-calcium in water ,is decreased due to drinking ROwater

2-difficulty in absorption of calcium

calcium is important for overall health. Almost every cell in our body uses calcium in some way. Some areas where our bodies use calcium is in our nervous system, muscles, heart and bone. Our bones store calcium in addition to providing support for our bodies. As we age, we absorb less and less calcium from our diet, causing our bodies to take more and more calcium from our bones. Over time this aging process can cause or contribute to osteopenia or osteoporosis.

📷We get calcium from the food we eat. Calcium-rich foods include milk, cheeses and other dairy products. We can also get calcium from vitamins and supplements.

📷Our bodies like to keep the amount of calcium in our blood within a certain narrow range. This range allows the cells in our body to stay healthy and perform jobs necessary for life. When blood calcium levels are low the amount of calcium in our blood goes below normal, our parathyroid glands release a hormone called parathyroid hormone (PTH). Although this sounds similar to thyroid hormone, PTH is different. PTH tells our bones to release more calcium into the blood stream. PTH also helps activate vitamin D which in turn increases intestinal calcium absorbtion.

📷We obtain vitamin D from the foods we eat and from our skin in response to sunlight. so we should analyse blood to see deficiency of calcium

We still in need for calcium as in late time we cannot take calcium ,we need 1000 ppm of calcium ,se we should take 1000 milligram each day .

Calcium is needed for bone building and supporting.