You can try BMC biology (IF 7.5). This journal proposes methodology articles.

Nature Methods main focus on methods and requires a significant amount of data to back up your method.

I would also suggest the "journal of cell science" (2013 IF 5.3, 5-year IF 6)

Cell Reports (http://www.cell.com/cell-reports/home) and

Scientific Reports (http://www.nature.com/srep/index.html)

come to my mind...

Molecular Biology of the Cell (IF ~6)

Journal of Cell Biology (IF~10)

Nature Communication (IF~10)

thank you for the helpful answers.