Can anyone please explain which type of structure is preferred for a ligand-Receptor docking study? When both the NMR based and X ray crystallography based structures both are available in PDB?
Dear Mahapatra,
An X-ray will be a better option for you, but once the resolution varies a lot and the missing items are many, it would suggested to use an NMR structure.
X-ray will be better for you but X-ray structures have certain artifact's ull have to remove it by manually with any of the offline softwares
In general X-Ray should be better resolved, but why not to use both ... as it is a in-silico? Maybe you learn something....
Alfred
X-ray-based structures are preferred because of their higher resolutions
Its X Ray Crystallography only as thumb rule however now a days small amount of data is also available by NMR & Cryoelectron microscopy
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