Which software do you use to analyze loss-of-heterozygosity?

Domenico Vladimiro Libri @Domenico_Libri

01 January 2013 1 2K Report

I have 32 patients genotyped with Illumina Quad-Chip 660W and I need an open source software to analyze LOH in my patients. Could anyone help me?

Corinna Ernst

As far as I know, most of recent software for the purpose of LOH detection is adapted to wg or exome sequencing data.

However, maybe LOHAS (Loss-of-heterozygosity analysis suite) meets your requirements:

http://www.stat.sinica.edu.tw/hsinchou/genetics/loh/LOHAS.htm

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