Which program cell death pathway play a major role in eliminating germ cell from mammalian ovary?

28 April 2020 0 4K Report

Several death pathways have been operated in mammalian ovary to selectivel eliminate surplus, defective, unwanted, damaged and abnormal germ cells from ovary but the contributiin of each pathway remains to be established.

Badges
Science topic

Similar topics
Social Psychology
Attitude

More Shail K Chaube's questions See All

Does oocyte generated from Oocyte like stem cell/neo-oogenesis/adult oogenesis is as good as natural oocytes?

Our long standing understanding for mammalian ovary is that it has fixed number of germ cells and duty of the ovary is to ovulate high quality ovum for successful fertilization and early embryonic...

11 October 2021 957 8 View

Similar to sperm funtion test, do we have scope to develop a oocyte function test for the management of women's egg factor issues?

As we know that the sperms function test is widely used for the management of male factor issues worldwide. However, similar parallel test is not available for the management of egg factor issue...

08 October 2021 4,336 2 View

Can the shape, number and distribution of mitochondria be used as a biomarker for oocyte quality?

Recent evidences suggest that mitochondria play important roles in determining the quality and fate of the oocytes in several mammalian species. Changes in shape, number as well as the...

05 October 2021 4,617 4 View

Which one is responsible for meiotic resumtion in mammalian oocytes i.e. "maturation promoting factor (MPF) activation or MPF destabilization?

The maturation promoting factor (MPF) is a key regulator of cell cycle that has regulatory subunit (Cyclins) and catalytic subunit (Cdks). Dissociation and degradation of specific cyclin...

29 September 2021 3,902 5 View

Can anyone please suggest the research papers related to Crustal Deformation in Eastern Indian peninsular/Eastern Ghats/East coast of India?

There are many geophysical and remote sensing methods to determine the crustal deformation and active tectonic movements. I need some research papers related to active tectonic movements in...

19 January 2021 2,559 3 View

What are the latest advancements in computer-based SignLanguage Interpretation?

The Canadian Institute of Mass Communication (CIMCweb.com) is embarking on a pilot project to create language-barrier-free learning environment for deaf students, as a scalable model for...

28 July 2020 9,242 1 View

Is there any master switch that decides which death pathway will operate to eliminate a cell in mammalian tissue?

Type of insult (drugs, oxidants, intoxicants and other factors) and duration of exposure have been studies well to analyze the initiation of various death pathways (apoptosis, necrosis,...

13 June 2020 6,836 1 View

Can oocyte like cells generated through neo-oogensis undergo spontanous meiotic maturation in vitro?

Several studies indicate the presence of oogonial stem cells (OSCs) in postnatal mammalian ovaries. It has long been held that the ovaries contain a fixed number germ cells that remains...

05 June 2020 469 0 View

What structural differences enabled corina virus in rapid spread globally?

There are several pathogenic viruses but the way corona became pendemic remains mystry. Is it natural and came from animal origin or artificialy made so in the lab? Its spreading ability and...

18 May 2020 2,566 0 View

Does type and level of insult decide initiation of specific death pathway in mammalian cells?

Veriety of insult including stress initiate various death pathways in specific manner. It remains unclear whether specific type and its level decides which death pathway including PCD would be...

03 May 2020 3,672 0 View

Is there any way to quantify bacterial and fungal cells in their mixed culture?

I am working in fungal fermentation of soybean meal and there is bacterial growth in them at times. I am trying to quantify fungal cell counts and bacterial cells; but I haven't been able to do at...

07 August 2024 7,535 4 View

Why activated CAR-Jurkat cell could not kill targets?

Previously when I co-coluture anti-CD19(FMC63) CAR-Jurkat with Raji with E:T=5:1, Jurkat can eliminate Raji in 24h. However, when I test another CAR construct, although I can dectect totally CD69...

06 August 2024 641 2 View

How much total RNA concentration to be extracted from sorted plasma cells from bone marrow of C57BL/6 mice for RT-PCR ?

i have sorted anti-NP specific plasma cells from bone marrow of C57BL/6 mice at certain times after immunization with variable counts and isolated total RNA using TRIZOL method for RT-PCR using...

05 August 2024 8,835 1 View

How to use Density Functional Theory to calculate carrier mobilities of solid system?

Hello, everyone. I have tried to determine carrier motilities of some materials, by Density Functional Theory, using Quantum ESPRESSO. There are a few methods to do it, like a package called...

04 August 2024 8,894 1 View

Does long-term culture of murine Monocytes result in macrophage differentiation?

Hi, I am isolating monocytes from the bone marrow using the Mouse Monocyte EasySep kit. I want to treat these cells and monitor expression of specific markers over the course of 10 days. I will...

04 August 2024 7,282 2 View

How can I get my Granzyme B flow cytometry stain to be consistent?

I have used PE and PE-Dazzle 594 fluorochromes and have managed to get NK cells to properly show GranzymeB expression after 4 hr PMA/ionomycin stimulaton, but for some reason my CD8 cells in the...

01 August 2024 7,677 2 View

Best mask design for metal deposition aiming build a Perovskite solar cell device?

What types of mask designs for metal deposition, to be used in a PVD system, are best suited for perovskite-based solar cells?

31 July 2024 4,835 3 View

How to culture and maintain Lx-2 cells?

Hi there! I recently started working on Lx-2 cells. When I thaw the cells, they start attaching within few hours but later in about 2 days they started rounding and dying. I used DMEM+2% FBS...

31 July 2024 3,893 0 View

How to treat monolayer culture cell line with essential oil?

Hi all, may I ask you for advice about treating monolayer culture cell line with essential oil. Due to the hydrophobic character of the oil, I am concerning how can it equally affect to all the...

31 July 2024 5,301 2 View

Creating an Automaton/Using Language as the Model?

As animals learn a task, they become more reliant on their long-term memories as compared to the real-time sensory information to guide behavioral performance (Ahilan et al. 2018). This process...

31 July 2024 9,859 0 View