I have gone through many research articles for nano particle synthesis to across blood brain barrier (BBB) drug delivery. Finally i came to know lipid nano particles better and has less adverse effect to brain over other types. In some paper they given solid lipid nano particle is better for across BBB and some articles they given Liposomes are better for across BBB so, finally i got confusion. Would you please anyone suggest which is better among these and kindly give me easy preparation of working protocols for that if anybody is working in this.