Papillary thyroid cancer is a common endocrine malignancy, and the BRAF V600E mutation confers it with aggressiveness and metastatic potential. I need a proper cell line, to study this form of cancer.
I am just adding in the Cellosaurus the very detailed info in the very recent review paper:
"Comprehensive Genetic Characterization of Human Thyroid Cancer Cell Lines: A Validated Panel for Preclinical Studies"
DOI=10.1158/1078-0432.CCR-18-2953
and in term of PTC with a BRAF V600E I noted:
CUTC5:
https://web.expasy.org/cellosaurus/CVCL_W916
CUTC60:
https://web.expasy.org/cellosaurus/CVCL_VM61
Both cell lines have just been published in:
https://www.ncbi.nlm.nih.gov/pubmed/30733375
IHH-4:
https://web.expasy.org/cellosaurus/CVCL_2960
Available from JCRB
K1:
https://web.expasy.org/cellosaurus/CVCL_2537
Which is in fact GLAG-66 but which does not seem to be distributed.
LAM1:
https://web.expasy.org/cellosaurus/CVCL_W912
LAM136:
https://web.expasy.org/cellosaurus/CVCL_RP38
MDA-T120:
https://web.expasy.org/cellosaurus/CVCL_QW85
MDA-T32
https://web.expasy.org/cellosaurus/CVCL_W913
MDA-T41
https://web.expasy.org/cellosaurus/CVCL_W914
MDA-T85
https://web.expasy.org/cellosaurus/CVCL_QW84
All four MDA-Txxx cell lines are distributed by ATCC
Best regards
Amos Bairoch
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