I want to dock a protein that naturally binds with rRNA. Please suggest some good tools.
We have two variables X and Y. Analysis of different regression models shows that polynomial quadratic equation provides the best fit for Y with respect to X. Say, the equation is y = -0.0055x²...
01 February 2019 5,103 8 View
I have carried out a FASTQC analysis on raw reads of SAGE-RNASeq experiment from SRA database. Numerous overrepresented sequences have turned up pertaining to Illumina single end adapters and...
11 December 2016 8,331 0 View
Running a GNU parallel blast uses only ~2% of my memory per core. My system has a quad-core 24 GB RAM. 1.Can I affect the speed of blast process and reduce the time of run by alloting more memory...
08 September 2016 8,413 2 View
I am using R 3.2 and Rstudio in Windows 7. Since, I am using a proxy internet connection, I always get the 407 proxy authentication error. I have tried setting environment variables with my proxy...
01 February 2016 6,689 2 View
Please provide a minimal advisable requirement of RAM and CPU Cores. Also, provide the time (in hours or days) required per such assembly, if experienced.
01 February 2016 8,691 9 View
Is there a pipeline for such analysis?
01 February 2016 2,594 2 View
The field of non-coding RNA research is one of the quickly emerging areas in the world of science. Few years ago, we had just tRNA and rRNA; then suddenly we had ribozymes and now we have the...
09 October 2015 7,228 1 View
How does a grid cells get the information?
01 February 2015 5,525 4 View
I've to add a methyl group to the C-5 of a Uracil base in the 3D structure of an RNA molecule. Please suggest tools to do so.
06 July 2014 2,435 4 View
I have two Quad core HP Z400 workstations and two quad core Acer Veriton series with i3 processor.
04 May 2014 5,973 16 View
I have virus (viral hemorrhagic septicemia virus) in suspension and the experiment will not involve cells. What level of TCID50 is preferred?
11 August 2024 3,115 1 View
I would like to understand potential safety concerns while handling SEB in the lab. Especially while working in animal house facility. Would like to know precautions for handling. Sigma MSDS...
07 August 2024 6,034 3 View
During low-temperature testing, new diffraction peaks that appear could be indicative of several phenomena. In one of our tests, we observed notable new peaks around 40° and 45° in a specific...
06 August 2024 726 3 View
After immunohistochemistry of previously fixed in PFA and EtOH and then frozen 20 μm sections of zebrafish brain, DAPI staining is very weak (right) compared to the same sections stained without...
05 August 2024 9,637 2 View
I am working on Abaqus/Explicit(Quasistatic ) for the deformation of the auxetic structure model. Please explain how the plastic input value should be considered from the true stress-strain curve...
05 August 2024 454 3 View
I aim to be as skeptical as possible regarding whether a pair of orthologous genes results in the same phenotype in their different but related bacterial organisms under similar environmental...
05 August 2024 6,787 4 View
Brain and body mass together are positively correlated with lifespan (Hofman 1993). The duration of neural development is one of the best predictors of brain size, and conception is the best...
05 August 2024 6,247 3 View
I am working on a SEM model where i have 7 latent variables (6 exogenous and 1 endogenous). In AMOS when I co-vary the exogenous constructs, only 2 paths are coming significant out of 6. But when...
03 August 2024 6,028 4 View
Suppose I am studying the construct of "Academic Motivation" (latent variable) in students, which is measured through three observed variables: "Intrinsic Motivation," "Extrinsic Motivation," and...
31 July 2024 3,913 6 View
I am looking for software to help analyze SELEX NGS data, including alignment, sequence enrichment, and other related tasks. Can anyone recommend suitable tools or software? Best wishes, Waleed
30 July 2024 1,061 5 View