Yes this is the great potential area and will  resolve a lot of problem  including the fetal  blood groups. 

It would be ideal to use fetal cells circulating in the maternal system. Before Dennis Lo et al. found that there is placental DNA in the maternal system, some studies were made focusing on fetal cells. However, these cells are extremely rare and it is difficult to collect them. In addition they persist for years, so that you will find fetal cells in a current pregnancy that comes from a previous one. In terms of screening for trisomy, the results of these studies (NIFTY) were not that promising, in fact worse that first trimester screening. If however, it is possible to overcome these limitations, fetal cells could be a key towards screening for chromosomal defects and other disorders.

I agree Kagan. The other limitation is very difficult to ruled out a possible mosaicism, because are few cells and besides confined placental mosaicism in trophoblastic cells.

luis

Is there trophoblastic cells in the maternal cervix?

luis

Yes we can found trophoblastic cells in the maternal cervix. You can make non invasive prenatal diagnosis with this cells. Cioni et al. Prenatal Diagnosis 2005.

Dear  luis alberto mendez-rosado

Can  you please  provide us with  any link?

I send to you  2 abstracts down load from Pubmed

good luck

luis

Thanks luis

Dear Adam

I sent to you 2 summaries of 2 publications, but I have not access to full text, if you can down load this publications would you mind send to me?

thank you

luis