I want to dissect inguinal white fat in mouse, but I don't know where exactly it is. And I am confused whether posterior subcutaneous adipose tissue is the same with inguinal adipose tissue.
Chunlei Yuan, when you put a mouse in a supine position, inguinal adipose tissue is exactly the same with posterior subcutaneous adipose tissue. Please look at the picture in the link below:
inguinal depot extends from the base of the hindlimb ventrally across the groin and contains a prominent lymph node. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017470/
perturbations and that body fat distribution is an important determinant of obesity-related complications. Individuals with increased upper-body adiposity are disproportionately burdened by obesity-related diseases, compared to lower-body obese individuals. Thus, it is paramount that studies continue to elucidate the pathways linking various adipose pads and depots in relation to health and disease, as well as the mechanistic underpinnings dictating how body fat is distributed in order to answer fundamental questions. Rodents are commonly used to model features of human metabolism and obesity, yet it is unclear to what extent rodent fat pads are a suitable model of human fat depots. Here, we have highlighted examples of both shared and divergent traits among rodent fat pads and human fat depots. Given some of the stark differences in adipose tissue location and function among species, we urge careful consideration in experimental design and interpretation when attempting to draw definitive parallels between rodent fat pads and human fat depots.