Where is the inguinal white fat in mouse?

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Is it harmful to breed for Cre Homozygosity initially?

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Aminuddin Aminuddin

Chunlei Yuan, when you put a mouse in a supine position, inguinal adipose tissue is exactly the same with posterior subcutaneous adipose tissue. Please look at the picture in the link below:

https://www.ncbi.nlm.nih.gov/books/NBK555602/figure/obesity_adip-metab.F12/

Chinaza Godswill Awuchi

inguinal depot extends from the base of the hindlimb ventrally across the groin and contains a prominent lymph node. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017470/

Check https://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(17)30714-3

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835715/

Aref Wazwaz

Dear Dr Chunlei Yuan . See the following useful RG link: Article Sympathetic innervation of inguinal white adipose tissue in the mouse

Kindly see also the following good RG link: Article Developmental and functional heterogeneity of white adipocyt...

Also check please the following good RG link: Article Sympathetic innervation of inguinal white adipose tissue in the mouse

The following RG link is also very good: Article White Adipose Tissue Browning in the R6/2 Mouse Model of Hun...

Shakir M. S. Alfahdawi

perturbations and that body fat distribution is an important determinant of obesity-related complications. Individuals with increased upper-body adiposity are disproportionately burdened by obesity-related diseases, compared to lower-body obese individuals. Thus, it is paramount that studies continue to elucidate the pathways linking various adipose pads and depots in relation to health and disease, as well as the mechanistic underpinnings dictating how body fat is distributed in order to answer fundamental questions. Rodents are commonly used to model features of human metabolism and obesity, yet it is unclear to what extent rodent fat pads are a suitable model of human fat depots. Here, we have highlighted examples of both shared and divergent traits among rodent fat pads and human fat depots. Given some of the stark differences in adipose tissue location and function among species, we urge careful consideration in experimental design and interpretation when attempting to draw definitive parallels between rodent fat pads and human fat depots.