What is the status of malaria vaccine?

Malaria is the highest killer disease in Africa, yet no vaccine has been developed against it. Any hope in sight?

05 October 2020 5,670 7 View

I tried to run Ligplot+ version 2.2 for the first time on ubuntu 16.04 but it always report error: error writing parameter file. Can you help?

I downloaded a components.cif file and filled the location of my .pdb files as shown in the picture below. It still showed error. The program usually opens but doesn't display the pdb files I want...

25 May 2020 8,509 2 View

I tried metawin unfortunately I couldn't get much help on how to code studies. Does anyone know a good free package for correlation meta analysis?

By the way I also need advice on which correlations to extract from factor studies ( exploratory, confirmatory, & SEM PLS) for meta analysis?

16 March 2020 7,217 3 View

Who was DIMU in the history of Egypt? How is it linked to Kadimu of Siaya County, kenya?

there is a name called Kadimu bay in Siaya, kenya. However, there is also a historical figure called Dimu who seems to be related to the Luo. What is the link between the Egypt Dimu and the Kenya...

29 January 2020 5,176 1 View

Can one conduct a meta analysis on previous meta analyses?

When meta analyses on the same topic yield different results with no consensus, can one conduct a meta analysis on the Meta analytic studies?

19 December 2019 6,113 4 View

Is it possible to run mediation for a panel data?

I intend to run a sequential mediation for a study but am at a lost as to my data. My search shows process macro is not for panel data, but my data is panel. can i be assisted in running a...

28 May 2019 8,256 20 View

What is the effect of white spirit or petroleum spirit on the drying time of alkyd paints?

I desire to know the contributive effect of the solvent, white spirit oon the drying time of oil-based paints made from alkyd resiin

07 January 2019 5,695 1 View

Any alternate computer/software program, besides R-package or Xcalibre 4.2 for computing effect size within DIF?

The goal here is to provide my students with a relatively easy program to use for computing effect size estimates for DIF [item-level invariance] within IRT (parametric). Xcalibre 4.2 offers this...

20 June 2015 3,702 2 View

What is the population doubling time of mesenchymal stem cells derived from human bone marrow derived?

while calculating PD from which passage number should we take into consideration? Passage 0 (culture initiation) will not have the absolute MSC cell count since we just add Mononuclear cells from...

05 April 2015 8,561 5 View

Does media change or passaging of cells in cell culture reduce endotoxin levels?

Does culture passaging or media change reduce endotoxin levels?

29 December 2014 9,274 12 View

Why does blocking with my immunogenic peptide cause nuclear fluorescence in ICC?

Hi all, I am validating a polyclonal antibody raised against human ANT4, through WB and ICC. In most of my controls, the antibody shows very little off-target binding, but when I pre-incubate the...

03 March 2021 5,999 3 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

Help request in CST microwave?

im working now on TPV solar cells and metamaterials and i realy need our help in CST microwave i have a tpv cell simulation and i want to extract particullarly the absorbtion of only the active...

02 March 2021 2,246 2 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

How to avoid ulcers in s.c. injected tumors ?

Recently, we have injected s.c. B16F10 tumor cells in BL/6 mice. At around 12-15th day some animals showed ulcerations in tumors , with a big hole in the middle (it looks like a volcano). We have...

01 March 2021 9,938 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Dapi fluorescence protocol for colon cell lines ?

28 February 2021 2,534 2 View

Does RNAiMAX transfection reagent work in serum free medium?

I diluted siRNA and RNAiMAX in opti-MEM and added to the cells which they were in the growth medium. Is it a right way? or should I culture cells in the opti-MEM medium for a while and not in...

26 February 2021 10,041 3 View

Has anyone had luck using cell lines other than HEK 293 (such as COS1) to package lentivirus?

I am looking to package lentivirus in endothelial cells but I am opposed to using 293 cells due to personal ethics regarding the source. I have done some reading and saw that COS1, COS7, & CHO...

25 February 2021 3,030 1 View