Sorry that I’m not familiar with EU regulations but I can help with you with regs in the States. Check our this link from the US FDA (Food and Drug Administration), our regulatory body for medications.

FDA Drug Safety Communication: Prescription Acetaminophen Products to be Limited to 325 mg Per Dosage Unit; Boxed Warning Will Highlight Potential for Severe Liver Failure

https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-prescription-acetaminophen-products-be-limited-325-mg-dosage-unit

Hope that that helps.

Thanks, Donna Lisi I'll check out the site. Any little help is great.

Sorry, biut Paracetamol, actually is AN hepatotoxic drug not safe, even at "normal" doses, BECAUSE THE INSULIN RESISTANCE IN LIVER in a lot of women and men, specifically in American people. https://opastonline.com/wp-content/uploads/2018/07/paracetamol-and-cardiac-congenital-malformations-in-prediabetic-pregnancy-women-ijdmd-18-2.pdf

interesting!

I found these guidelines from the UK's National Health Service while looking for similar info. It's not a peer-reviewed paper, but since it's coming from a EU govt website, it might lend some credence:

https://www.nhs.uk/medicines/paracetamol-for-adults/

Here's a primary-source paper demonstrating the dangers of consuming more than 4 grams of paracetamol per day, which lines up with most dosage recommendations I've found:

https://europepmc.org/abstract/med/24779190

This next one is a peer-reviewed article in my own field (psychology). The study was conducted in the U.S., but I include it because they give a pretty thorough description of how to minimize risks of the drug (e.g., limiting the dose to 1g, excluding high risk groups such as those with liver disorders of APAP allergies, etc.). If I find any similar studies that were conducted in the EU, I'll pass them along.

https://academic.oup.com/scan/article/11/9/1345/2224135

Hope these help!

(PS, the FDA link that somebody else posted is for prescription medicines that contain paracetamol rather than paracetamol itself. So the 325mg limit is for combinations of paracetamol & opiates, for example)

(PPS, this European article about paracetamol pack size restrictions in different countries may also be useful)Article Availability of Paracetamol Sold Over-the-Counter in Europe:...