Eicosanoids are generated from fatty acids but I was wondering where this conversion takes place? In the cells or outside of the cells?
Dear Fa,
Eicosanoids are a group of signaling molecules that are derived from fatty acids. The conversion of fatty acids into eicosanoids takes place inside cells. More specifically, the transformation occurs within the cytoplasm or cellular organelles, such as the endoplasmic reticulum or the mitochondria.
Fatty acids are converted into eicosanoids by enzymes called lipoxygenases or cyclooxygenases. These enzymes catalyze the addition of oxygen molecules to the fatty acids, forming various eicosanoids, including prostaglandins, leukotrienes, and thromboxanes.
Eicosanoids play essential roles in various physiological processes, including regulating inflammation, blood pressure, and the functioning of the cardiovascular and respiratory systems. Different signaling pathways tightly control the production and release of eicosanoids. The specific eicosanoids produced can vary depending on the type of cell, tissue, and the presence of particular stimuli.
Yours sincerely,
Edgar M Cambaza
- Badges
- Science topic
- Similar topics
- Linguistics
- Composition Studies
- Publication