I am planning to do a CRISPR-Cas9 HDR based knock-in into the exonic region of my gene. Generally, it is well suggested that, for knock-in, using ssDNA as a donor template is very efficient rather than a plasmid vector. But, my insert region is 100% similar with the initial portion ( approx 100 bp) of one of the homology arm. Could it be problematic in case of knock-in the template? How can I avoid that? Any suggestion would be well accepted. I have attached a representative fig., in a doc file below.