Pathogens cause pathogenicity by acting on specific parts of the body or by manipulating different metabolic pathways in hosts. They do these with the expression of specific genes. If we can silence these genes, maybe we can stop the organism from causing pathogenicity.
Lab strains or lab grown strains do not cause diseases in real world anyway. The idea you are thinking about might be possible but not practical.
@ Araf, you may use the methods such as RNAi, CRISPR, or siRNA to reduce gene expression but you can reduce up to 70%, 100% reduction is not possible.
I add to the last answer that some pathogens have genomic plasticity, which means, they mutate on condition to adapt to survive. Genetic editing tools can have good results in some cases but can lead to seriously negative results depending on their handling.
A pathogen is a species within an ecosystem. By extinguishing this species, cannot nature replace it with something that can be even worse? It's just a reflection, I know these tools excite us for their accuracy but science requires time, efforts, and patience.
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