The solvent choice for 4,4'-dicarboxy-2,2'-bipyridine (4,4'-bpy) depends on the specific application and the desired outcome. 4,4'-bpy is soluble in a range of organic solvents, including polar solvents such as dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF), as well as non-polar solvents such as tetrahydrofuran (THF) and chloroform.
In some cases, the choice of solvent can affect the stability and solubility of the 4,4'-bpy and its reaction products, so it is important to carefully select the appropriate solvent for each specific application. The selection of the solvent can also impact the reactivity, solubility, and purification of 4,4'-bpy and its derivatives, as well as the ease of handling and the safety of the reaction.