Bioconjugation
Sodium cyanobohydride es a reductant, it transfer hydride to imine.
For example in this paper
http://pubs.acs.org/doi/abs/10.1021/bc400018u
Aldehyde reacts with the terminal amine to form and imine that is reduce to an amine,
you end having a C-N bond That is a reductive amination reaction.
Dear Pooja Nanda ,
Sodium cyanobohydride is just reduce the amine to imine., its just reductive amination main agent out of that no role for this., without this only 20-30% of reaction yield we will receive.,
Good Luck & Regards
R.Selva....
yah i agree R.Selva.. and Guillermo R. Labadie answer
Dear Selva,
Thanks for the information.
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