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Krishna Kumar Govindarajan

Decision making regarding use of antibacterial prophylaxis involves weighing measures of efficacy against potential negative consequences.

Measures of efficacy of prophylaxis include reductions in fever, bacteremia, sepsis, infection-related mortality, and overall mortality.

Potential negative consequences of prophylaxis include Clostridioides difficile infection, invasive fungal disease, drug toxicities, and antibiotic resistance.

Thanks Ms. Gehan Abdel Naser . How common is the practice of antibiotic chemoprophylaxis in your experience? Also, would be interesting to know the actual outcome / data regarding this.