What is the percentage of Her2 overexpression in PDAC?

10 June 2018 1 7K Report

what is the percentage of Her2 overexpression in PDAC?

Accoring to Yamanaka et al (1993)

HER2/neu immunoreactivity was expressed in 34 of 76 (45%) pancreatic carcinomas.

Northern blot analysis indicated that HER2/neu mRNA levels were elevated in 13 of 25 (52%) of the tumors in comparison with the normal tissues.

Which one is more accurate?

thanks

Eya Wolfson

One is referring to protein levels, the other is referring to mRNA levels, neither is more accurate, each concerns a different molecule :)

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