A new variant strain of SARS-CoV-2 that contains a series of mutations has been found in the UK and become highly prevalent in London and southeast England. Based on these mutations, this variant strain has been predicted to potentially be more rapidly transmissible than other circulating strains of SARS-CoV-2. At this time, there is no evidence that this variant causes more severe illness or increased risk of death.
At present, the variant is referred to as “SARS-CoV-2 VOC 202012/01” or “B.1.1.7."
This variant has a mutation in the receptor-binding domain (RBD) of the spike protein at position 501, where amino acid asparagine has been replaced with tyrosine (N501Y). This variant carries many other mutations, including a double deletion (positions 69 and 70).
A new variant of the pandemic SARS-CoV-2 coronavirus is spreading rapidly in Britain and prompting high levels of concern among its European neighbors, some of which have cut transport links.
There's no evidence to suggest the vaccine will be any less effective against the new variant. So don't worry and stay safe. Follow the protocol to avoided the spread.
A scary new strain of coronavirus, innocuously named B.1.1.7, has recently exploded across southeast England, prompting the government to tighten lockdowns on the region. Though we don't know all the details, experts are increasingly confident it is more easily transmitted than other strains. The B.1.1.7 strain of SARS-CoV-2 is a version of the virus with 23 mutations, eight of which are in the spike protein the virus uses to bind to and enter human cells. It was first detected on Sept. 21 in Kent County in England, then took off and spread in November. Since then, it has become the most common variant in England, representing more than 50% of new cases diagnosed between October and Dec. 13 in the U.K., according to the WHO. However, some scientists now believe that the virus may have mutated in a person who was immunocompromised. That's because, unlike the flu, the novel coronavirus can correct mistakes when it replicates, and so tends to have a fairly stable genome, Live Science previously reported. However, studies have shown that people who have weakened immune systems — because they are taking immunosuppressant drugs or are being treated with chemotherapy, for instance — may harbor the infectious virus for months.