I prepare some nanoparticle by emulsification solvent diffusion method with PLGA and PVA and some kind lipid,but I do not know the products are nanocapsules or nanosphere?
In general, emulsification solvent diffusion method produce nanospheres, however the situation here will be different as you used lipid-polymer mi. I think it will produce a nanocapsule with a polymeric membrane and oily core. This might be clear after doing TEM or AFM analysis.