From a hosts point of view, which comes first, effect of toxins on pathways or identification of toxins?

From a pure biology perspective, when a pathogen affects a host, what comes first, the effect of the toxin (effector protein) on the pathways or identification of the structure of the toxin by the...

01 February 2020 8,453 6 View

How do you apply statistical testing when predicting effector proteins?

Being a computer science student, I don't know much about statistical testing. However, recently, a lot of work has reported statistical validation of their result. In machine learning-based...

10 November 2019 6,264 2 View

How to download from NCBI the FASTA of all sequences for a particular search term?

After a search term is entered, on the top right there is an option called Send to. Then click File, and click FASTA under format tab. There they show you how many entries/sequences to be...

05 June 2019 6,191 2 View

Someone help me to find one gram-positive non-pathogenic bacteria residing in human gut along with a reference claiming the same?

I want to know the names of a few species of gram-positive bacteria which are non-pathogenic and and lives in the human gut....

04 May 2019 9,236 2 View

Where can i get all the proteins (amino acid sequence) and their corresponding nucleotide sequence of Bacillus subtilis?

I want a list of all the peptide and their corresponding nucleotide sequences of Bacillus subtilis In the fasta format.

04 May 2019 4,431 3 View

What is the example of a gram-positive non-pathogenic bacteria?

I want to know the names of a few gram-positive non-pathogenic bacteria

04 May 2019 8,244 2 View

How do I get the corresponding nucleotide sequence of a given peptide sequence?

Suppose, I have a peptide sequence, and I want to find out the corresponding nucleotide sequence of that peptide sequence. Is there any tool that finds this out?

03 April 2019 1,752 3 View

In order to establish a new metric for quantifying something, what are the prerequisites?

Suppose I want to establish a new metric for a certain bioinformatics problem. What are the mathematical prerequisites for establishing this metric? Are lemma's and theorems required for...

01 February 2019 1,953 2 View

How does binding between 2 proteins occur?

Suppose 2 genes produce 2 proteins which would be binding. After the genes are turned on and the proteins are produced, then genes can be turned off and the proteins produced can bind with each...

01 February 2019 8,742 6 View

When a protein binds to the dna or a particular gene, does the gene need to be activated in order to bind?

So proteins bind to DNA or genes all the time. I wanted to know whether before binding with a protein, the gene needs to be activated or not. If there is a research article backing your claim,...

31 December 2018 1,180 3 View

error in running a model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

error in modelling model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MGL tools

20 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

i have some problem with chtMultiRegionSimpleFoam

--> FOAM FATAL ERROR: Maximum number of iterations exceeded From function Foam::scalar Foam::species::thermo::T(Foam::scalar, Foam::scalar, Foam::scalar, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar) const) const [with Thermo = Foam::hConstThermo >; Type = Foam::sensibleEnthalpy; Foam::scalar = double; Foam::species::thermo = Foam::species::thermo >, Foam::sensibleEnthalpy>] in file /home/ubuntu/OpenFOAM/OpenFOAM-4.1/src/thermophysicalModels/specie/lnInclude/thermoI.H at line 66. FOAM aborting #0 Foam::error::printStack(Foam::Ostream&) at ??:? #1 Foam::error::abort() at ??:? #2 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::calculate() at ??:? #3 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::correct() at ??:? #4 ? at ??:? #5 __libc_start_main in "/lib/x86_64-linux-gnu/libc.so.6" #6 ? at ??:?

24 March 2021 0 0 View