From a hosts point of view, which comes first, effect of toxins on pathways or identification of toxins?

From a pure biology perspective, when a pathogen affects a host, what comes first, the effect of the toxin (effector protein) on the pathways or identification of the structure of the toxin by the...

01 February 2020 8,453 6 View

How do you apply statistical testing when predicting effector proteins?

Being a computer science student, I don't know much about statistical testing. However, recently, a lot of work has reported statistical validation of their result. In machine learning-based...

10 November 2019 6,264 2 View

Someone help me to find one gram-positive non-pathogenic bacteria residing in human gut along with a reference claiming the same?

I want to know the names of a few species of gram-positive bacteria which are non-pathogenic and and lives in the human gut....

04 May 2019 9,236 2 View

Where can i get all the proteins (amino acid sequence) and their corresponding nucleotide sequence of Bacillus subtilis?

I want a list of all the peptide and their corresponding nucleotide sequences of Bacillus subtilis In the fasta format.

04 May 2019 4,431 3 View

What is the example of a gram-positive non-pathogenic bacteria?

I want to know the names of a few gram-positive non-pathogenic bacteria

04 May 2019 8,244 2 View

How do I get the corresponding nucleotide sequence of a given peptide sequence?

Suppose, I have a peptide sequence, and I want to find out the corresponding nucleotide sequence of that peptide sequence. Is there any tool that finds this out?

03 April 2019 1,752 3 View

In order to establish a new metric for quantifying something, what are the prerequisites?

Suppose I want to establish a new metric for a certain bioinformatics problem. What are the mathematical prerequisites for establishing this metric? Are lemma's and theorems required for...

01 February 2019 1,953 2 View

How does binding between 2 proteins occur?

Suppose 2 genes produce 2 proteins which would be binding. After the genes are turned on and the proteins are produced, then genes can be turned off and the proteins produced can bind with each...

01 February 2019 8,742 6 View

When a protein binds to the dna or a particular gene, does the gene need to be activated in order to bind?

So proteins bind to DNA or genes all the time. I wanted to know whether before binding with a protein, the gene needs to be activated or not. If there is a research article backing your claim,...

31 December 2018 1,180 3 View

What is the impact factor of journal of bioinformatics and computational biology (world scientific)?

Got a research gate score, but I want to know its actual impact factor. Is it a good journal in Bioinformatics?

10 November 2018 2,063 3 View

How to analyze a particular region of my simulation box in GROMACS?

Hi, I am using GROMACS 5.1.4 to simulate water in contact with a surface. I am only interested to calculate some properties of water near the surface. Let's say at a distance of x nm from the...

03 March 2021 9,989 2 View

How to get onecolumn document from standard IEEE ACCESS LateX template?

I have prepared a manuscript in IEEE Latex template, but for some purpose, I need to prepare a word file as well (detailed format is not required). Compared to two column .tex file, one column...

02 March 2021 1,830 3 View

How can the modification of garden soil cause global warming?

Hello, I am working on a soil project and I found a primary research article that tests how the modification of agricultural soil can cause global warming, using a thermal collector, however I...

02 March 2021 7,161 3 View

Does anyone know how to plot my station to a section plot on Ocean Data View (ODV)?

I made a vertical section plot with WOA .nc file on ODV, and now I want to plot my stations (csv. file) in it. Does anyone know how to import my points to the section? They are two different...

01 March 2021 3,610 1 View

Does anyone know to clarify these changes?

01 March 2021 1,290 2 View

How can I convert .vesta file to a .cif file?

I've used the "export data" option in Vesta software to convert my unit cell into a cif file however when I use that cif in atomsk it shows error such as "can't read the position of atom 0". If I...

28 February 2021 4,966 3 View

How can we use a hybrid element in Abaqus Dynamic/Explicit for impressible materials?

Hi, all! How can we use a hybrid element in Abaqus Dynamic/Explicit for impressible materials? I have not find the choice for explicit element in Abaqus CAE. I am wondering whether it is possible...

25 February 2021 9,936 2 View

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25 February 2021 5,713 1 View

Anyone that can help with Maxquant TMT16plex which is missing?

Hi I am very new to proteomics analysis. I have got raw files from core facility running thermofisher TMT 16plex 4 hours. I cannot find on maxquant the option TMT16Plex there is only up to 11...

25 February 2021 1,675 3 View

How to search for crystal structure for material with atomic position labelled?

I am using the crystallographic open database and materials project to search for cif file but the exact structure is not mentioned or how can I deduce that the given structure and atomic position...

23 February 2021 6,723 2 View