Many prefer Inj. Adenosine - Needs Central venous / intra atrial administration owing to its very short half life. Inj. Amiodarone has an unpredictable half life. What next ?
Dear Muralidharan R.s.,
Drugs that can be used to terminate an attack include adenosine, calcium channel blockers (eg, diltiazem, verapamil), beta-blockers, and digitalis.
Adenosine
Adenosine is the first-line drug used for termination of AVNRT. In rare cases, the administration of adenosine may lead to atrial fibrillation or even asystole for a short period.
Adenosine administration should be given through a central, large bore intravenous (IV) needle, as it has a very short half-life. It should be followed by a saline flush and elevation of the extremity in which it is being injected. The initial dose is 6 mg followed by 12 mg and occasionally 18 mg. It should not be used in heart transplantation patients, it may be ineffective if given to a patient taking theophylline, and it may be potentiated by dipyridamole.
Preventive therapy
Preventive therapy is needed for frequent, prolonged, or highly symptomatic episodes that do not terminate spontaneously or for those that cannot be easily terminated by the patient. Drugs that are used for prevention of recurrence include long-acting beta-blockers, calcium channel blockers, and digitalis.
http://emedicine.medscape.com/article/160215-treatment#d10
Hoping this will be helpful,
Rafik
Sir, please check it.
emedicine.medscape.com/article/160215-overview
circ.ahajournals.org/content/107/8/1096.full
www.pharmacytimes.com/.../managing-and-preventing-supraventricular-tachycardia
Adenosine and calcium-channel antagonists have both demonstrated efficacy. See attached.
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