Your question are too general. The results are depending on the property of your specimen. If your specimen is compatible with the medium, eg. microbial strains in their favored medium, the quality of the extracted DNA won't be affected, you can spin down the cells, wash them for several times to get rid of the medium before DNA extraction.  If not compatible, the cells of your specimen will be broken and DNA will be digested by DNAse present in the medium.

In the course of evolution, bacteria have developed the ability to synthesize so-called restricteduse enzymes (endonucleases), which became part of the cell (bacterial) system restriction-modification. In bacteria systems of restriction-modification of intracellular immune system protection from alien DNA. Unlike higher organisms, in which the recognition and destruction of viruses, bacteria and other pathogens occurs extracellular, bacteria protection against foreign DNA (DNA of plants and animals, in the body they inhabit) is intracellular, i.e., when foreign DNA enters the cytoplasm of the bacteria. To protect the bacteria in the course of evolution, have developed the ability to "mark" their own DNA mahilyouski bases on certain sequences. For this reason, the alien DNA due to the lack of a metal of groups on the same sequences melts (cut) into fragments of different bacterial restrictase, and then are degraded by bacterial ectonucleoside to the nucleus of the Chida. We can say that in this way the bacteria protect themselves from the DNA of plants and animals, in the body they inhabit temporarily (such as pathogens) or permanently (as saprophytes).

Restrictase were first isolated from E. coli in 1968 - was that they are able to cut (melting) of the DNA molecule at different sites (locations) restriction. These enzymes called endonucleases class I. Then, at the bacteria were detected class II endonuclease, which recognizes in alien DNA restriction sites and specifically on these sites also provide restriction. It is the enzymes of this class were used in genetic engineering. At the same time were discovered enzymes of class III, which is melted DNA near the site of recognition, but these enzymes are not important in genetic engineering.

The system of restriction-modification "rationalized" so-called palindrome (recognizing sequences of nitrogenous bases, which are the sites of restriction analysis of DNA. Palindrome sequence is a base sequence that is the same read forwards and backwards, as, for example, the sequence of letters radar. Because the DNA chain have antiparallel direction, it is considered that the sequence is palindrome if it is the same when read in the direction from 5'- to 3'-end on the top and 3'- to'-end on the bottom of the chain, namely:

Palindromes can be any size, but most of those palindromes, which are used as sites of recognition by restrictase consist of 4, 5, 6 or less 8 grounds.

 Restrictase is an absolutely necessary tool in genetic engineering to cut interest fragments (genes) of large DNA molecules. Since you know more than 100 enzymes, it allows the selection of restricted and selective cutting of fragments from the original DNA.

A remarkable feature of restricta is that they produce sections of molecules into several fragments (plays the guitar and sings tov) DNA ledges, resulting in the formed ends of one strand longer than the other, forming a kind of tail. Such ends (tails) is called "sticky" ends , because they are able to semiconcentrated.

 Consider the results of the restriction on the example of one of the most famous restricts Eco RI of the system restriction-modification of E. coli. Instead of melting of DNA in Central PA-syndromes sequence recognition, this enzyme melts the DNA outside the centre, and produces 4 semicomplete ("sticky") end consisting of a different number of the nucleus-Chida, namely:

 These "sticky" ends in genetic engineering experiments are useful for the reason that they can be reunited complementary at low temperatures, which allows for effective joining of DNA fragments.

 The recognition sites and the sites of fusion in the case of other restricts have other content, namely:

After restriction of DNA from a restriction mixture allocate restriction DNA fragments (DNA restricti), which then necessary to combine with the vector. For DNA-restricted resort to electrophoresis, because with this method restrictional DNA is very easy to fractionate by size slices restrictive and thanks to constant relations electric charge-mass. Fragments migrate in an electric field during electrophoresis at a frequency dependent on their size (mass). The more (longer) fragment, the slower it migrates in an electric field. Material, which carry out electrophoresis, are naturegeoscience agar and polyacrylamide. To identify fragments use these-Dios bromide, which paints the fragments, making it easier to detect .

The results of electrophoresis is very high, because it can be divided into fragments of a size of from 2 to 50, 000 grounds.

After electrophoresis the fragments from agarose allocate using different methods. Based on the results of comparison of the sizes of restrictive the same DNA obtained using different restrictus, construct restriction maps, which show the restriction sites of each of the used restricted . In practical terms, restriction maps allow you to determine not only the size of restrictive, but also to find out the location in the DNA loci of certain genes.

Because of higher organisms during transcription is synthesized heterogeneous DNA, correct processing, genetic engineering is usually used complementary DNA (cDNA), which is obtained by using as a matrix mRNA, in which the reverse transcriptase synthesizes single-stranded DNA (cDNA), which is a copy of mRNA. Subsequently, these single-stranded DNA is transformed into double-stranded DNA. Believe that the cDNA contains a continuous nucleotide sequence (transcribed and translated). It cDNA used for restriction analysis.

Selected after electrophoresis of agarose gels DNA fragments (restricta) can be pre-expose sequani application, i.e., to define them in the nucleotide sequence. This is done using chemical and enzymatic methods sec-generowania.

The chemical method is based on obtaining labeled with radioactive phosphorus (R) fragments and the removal of these fragments of one of the grounds followed by inclusion of the results of autoradiography of gels containing these fragments. The enzymatic method is based on the fact that at the end of the analyzed fragment is administered nucleotides, which are then used in the synthesis of different fragments in vitro, and analyzed for nucleotide sequence electrophoretic. For the study of the specific sequences of nucleotides in a DNA molecule used as the hybridization DNA-DNA, RNA-RNA, DNA-RNA, Northern and southern blotting.

Successes A. P. Biology of the basics of ecology. The series of Textbooks for higher education. Special literature" - 2000.

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Try to keep the DNA isolated from cells in pure water - without destroying enzymes DNA into nucleotides.

Since you are hiding many things in your question; it is rather difficult to answer you precisely. For example: What was the fermentation all about? What is the biological specimen you are referring to? Let me tell you that in a routine fermentation, with bacteria or fungi normally it should not affect. However, it is well known to all fermentation technologists that how so ever, one is claiming the culture to be pure, it is often contaminated with a virus. Secondly, during the several life cycles of the microbe, several things will happen like simple conjugation or transduction and then, the picture will change (of course, ultimately the frequency of these phenomena is important too). lastly if not the least, the stress that the organism underwent (if any) during any stage of its growth. Like these there are several other phenomena that could take place during a fermentation process which may or may not affect the quality of DNA.  

Sorry, I read that DNA is dissolved (loses structure) in water. Does maybe DNA study in the nucleus of cells that can be isolated (taken) out of the cell? I can say that there is a modern device that extracts DNA: The FastPrep-24™ 5G. This organization "MP Biomedicals Europe" can be found in the search of google or yandex.

Please see the edited description again if it clarifies the question. Thank you.

I think this question is linked with a collection of an organism found by chance on a picnic / excursion etc; where you don’t go for the collection. However, you can’t resist to loose this chance; unfortunately, You have nothing to keep that but a poor bear cane, till to return home.

If it is such; nothing harm, wash well the sample with D.O. water several times then make your dna extraction

I have preliminary data to suggest that collection of insects in beer reduces DNA extraction yield compared to those insects collected by hand and put directly into 70% EtOH.