In the literature, LNCap is lymph node metastasis cell line obtained from Caucasian male and LNCaP-LN-3 is metastatic subline of LNCaP cells derived by orthotopic implantation.
I want to know the difference between two cell lines. Most of prostate cancer model mentioned in the literature is made using LNCaP cell line.
In our laboratory we have LNCaP-LN-3 cell line.
Can prostate cancer model be made using LNCAP-LN-3 cell line? and it will be the same with LNCaP?
Previously we couldn't able to develop tumor model in nude mice using LNCaP-LN-3
any insight is highly appreciated,
Regards,
Briefly, LNCaP is poorly metastatic and LNCaP-LN3 is highly metastatic
In the archive (in attachment) has more information, details and differences subtle among types of CaP celles.
Kunal Pal, other than what Cassio wrote, why is lncap-ln3 is more suitable?
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