Does anybody know of recent or current comparison studies between the effects of bacteriophage therapy and that with antibiotics?
Hi, Steph,
My colleagues and I recently presented at ICAAC about using phage K and phage Msa (two lytic phages of S. aureus) against MRSA (and MSSAs, but antibiotics vs. phages looks like what you're interested in) isolates. The poster is available for a download from my publications page.
A group led by Vincent Fischetti has done a lot of work on using purified lysins from Streptococcal phages as a possible treatment for lots of different gram-positive infections (at least including streptococci and staphylococci) and I think have compared antibiotics to phage lysins. They presented tons of things on this at this year's ICAAC also.
Feel free to e-mail me for more. I love chatting about the phages!
Best,
Dr. Rachel L. Robson
Also...you probably already know this, but just in case you didn't...There was a lot of research on the potential of phages to treat infections done in the early part of the 20th century (look up Felix d'Herelle, he was an early leader) and then in the 1990's through today in eastern Europe (especially Russia.) The popular undergraduate microbiology textbook author Jacqueline Black has done a fair amount of work with some of the Russian phage researchers.
Hope this helps your literature search!
This is excellent! Thank you so much for your help... no doubt I will be contacting you with more questions within the next few months! Steph
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