What is the best method to get a smaller size particle when using medium molecular weight chitosan (Sigma product)?

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Ravi Teja Reddy

I am also facing same kind problem

Denish Kubavat

You may use methacrilic acid at place of acetic acid

Ramkumar Ponnuraj

This article may help you a bit even if it doesnot answer your query

Vinod Saharan

Dear Sir,

You may use our protocol for making chitosan NPs. See following publication for our Lab.

Article Synthesis of chitosan based nanoparticles and their in vitro...

Article Synthesis and in vitro antifungal efficacy of Cu–chitosan na...

Chapter Synthesis of Chitosan-Based Nanomaterials

Book Chitosan Based Nanomaterials in Plant Growth and Protection

Alaa Riezk

I have got the same issue with my particles size, so please did you find any thing that might help?.

Thanks