Ravi Teja Reddy

35 Questions 24 Answers 0 Followers

Questions related from Ravi Teja Reddy

What was pros and cons of Multispectral and hyperspectra lmage analysis for agriculture crops?

Difference between Multispectral and hyperspectral image analysis in agriculture crops.

08 August 2019 1,493 4 View

How to prepare 7.4 ph phosphate buffer?

how to use buffer equation for preparation of 7.4 pH buffer.

08 August 2016 1,128 3 View

Can anyone one explain methods for degas buffer or solvent?

i want remove co2 from buffer

08 August 2016 10,026 3 View

What are nutritional markers in saliva for obese people?

how to find genomics in obese patients with saliva sample

08 August 2015 6,950 3 View

Where can i get info on digital medical devices for public use?

i want know about how healthcare technology affecting people lives

06 June 2015 9,486 2 View

Can anyone please provide inputs on six sigma black-belt in pharmaceuticals?

how to implement six sigma in pharma industry

03 March 2015 8,361 3 View

How do drugs get entrapped into core nanoparticles,instead of high surface forces?

Nanoparticle surface forces are more when compared to body forces so how do drugs get entrapped in to core

09 September 2014 1,362 3 View

How does one ensure the stability of nanoparticles in in-vivo?

Nanoparticles are colloidal range, their stability is depend on the zeta potential that is based on surrounding fluid around particle. when it enter in to stomach or blood medium composition will...

09 September 2014 4,318 7 View

How can I control the agglomeration of nanoparticles in stability studies?

I prepared chitosan nanoparticles. I am conducting stability studies at two different zone temperatures, one is at 2 centigrade and another temperature is 25 centigrade. Nanoparticles at 25...

07 July 2014 891 7 View

Which is most reliable method for conversion of crystalline compound in to amorphous form?

several method available for conversion of physical state of the compound among which is best to retain permanent amorphous form

07 July 2014 2,442 14 View

What is most accurate technique for identification of crystallization in polymer mixtures?

In polymer mixtures during melt extrusion the physical state of polymer is changes (very rapidly to slow) in given time frame. Some are occur in initially nanometer range further spreads bigger in...

07 July 2014 9,446 12 View

How does one cease(stop) molecular motion of polymers during hot melt extrusion of the polymer mixture?

In hot melt extrusion, changes in molecular mobility lead to the changes in the physical transition of drugs.

07 July 2014 4,339 1 View

Does anyone have a suggestion for zeta-potential measurement by using surpass electrokinetic analyzer?

I did chitosan nanoparticles after I obtained solid particles. I did coating with Eudragit s-100 polymer so I want measure surface zeta-potential of both products. Please provide me with the details.

02 February 2014 6,124 0 View

What is the acceptable limit polydispersity index (pdi) of nanoparticles? And why?

I prepared chitosan nanoparticles some have got 0.2 and others are in the range of 0.4 - 0.5.

02 February 2014 1,032 31 View

Are nanoparticle size results reproducible?

I did chitosan nanoparticles, for each sample I did "three replicates malvren zetasizer that the three results are incomparable." What is reason behind it?

02 February 2014 1,156 12 View

How to characterize the pH sensitivity of nanoparticles?

I have prepared the pH sensitive nanoparticles and want to check their pH sensitivity.

01 January 2014 9,590 7 View

Why do chitosan nanoparticles show two peak size distribution peaks?

I am using chitosan polymer for naoparticles and I adopted ionic gelation method, but during particle size analysis it shows two peaks: one at 380nm and another at 4800nm but it does not shows...

01 January 2014 6,655 5 View

Are atomic force microscopy (AFM) results more accurate than DSC for physical stability of a solid dispersion?

I found in an article that if crystallization area below 30 nm DSC can not find the crystallization in solid dispersion, but DSC is a very promising tool for characterizing the polymer blends.

01 January 2014 9,179 1 View

How can we get an amorphous mixture after extrusion without crystals?

I am doing some work on miscibility and re-crystallization of amorphous drugs. I want to know about the effect of cooling rate on crystalline kinetics.

01 January 2014 8,142 5 View

Is Tα(alpha) equal to Tg(glass) temperature in an amorphous polymer?

I want know about the relation between Tα and Tg in both amorphous and crystalline polymers.

01 January 2014 5,091 5 View

What is the relation between molecular mobility and relaxation of polymers and how can we characterise these two parameters?

I'm struck with these relaxation kinetics and molecular mobility.

01 January 2014 6,050 8 View

Which parameters can we identify by interpreting dsc spectra?

I did dsc analysis for my drug and drug-polymer mixture, and seeking to learn about interpretation.

01 January 2014 7,919 10 View

How capping agents effect the zeta potential and colloids agglomeration?

Some researchers suggest adding some capping agents to increase the zeta potential. Does anyone have examples of positive zeta potential capping agents?

01 January 2014 6,143 0 View

What is the best way to identify the nanoparticles agglomeration strength?

Apart from from particle size measurements are there any other techniques for agglomeration strengths and agglomerates?

01 January 2014 7,826 10 View

How we can study the surface morphology and monodispersity of nanoparticles?

I want to know about the particle shape and either these are mono disperse or agglomerated.

01 January 2014 1,316 7 View

What is the importance of interaction of polymers and drugs?

Every time we do any formulation before we conduct interaction studies of a excipients and drugs.

12 December 2013 3,548 3 View

Why are the solubility parameters used to measure miscibility of polymer intern of physical stability of solid dispersion?

Various solubility parameters are used to determine miscibility of drug in polymer in solid dispersion. How can we conclude miscibility by using solubility parameter?

12 December 2013 2,393 8 View

Can anyone explain how we can determine the miscibility and physical state of drug in polymer mixture?

Some articles show that DSC can not give the details about miscibility of drug and miscibility effect drug release from polymer.

12 December 2013 980 5 View

Can anyone explain if only amorphous materials show the glass transition temperature(Tg) and why?

we use the term Tg for amorphous materials

12 December 2013 2,090 20 View

What kind of interactions are there between drug and polymer so that the drug remains in supersaturated state in gastric fluids?

Solubility and drug absorption in gastrointestinal tract is increased by supersaturation of drug in GI fluids. How can we maintain supersaturated state and without getting the drug being precipitated?

12 December 2013 4,731 1 View

What are the analytical methods to determine the Bio-distribution of drug loaded nanoparticles ?

I prepared nanoparticle formulation of Ciprofloxacin hcl for that I want the in vivo accumulation (or) distribution studies in rats.

12 December 2013 6,808 1 View

What is the best method for determining the solubility of bulk drugs as well as nano particle formulation of the same drug?

I select poorly water soluble drug that I want to increase solubility by nano particle formulation by decreasing size of particle solubility is increased so I want to measure solubility practically.

11 November 2013 428 1 View

How should interactions (physical or chemical) between excipient and drug during the formulation be understood?

I am formulating nano-particles so what are different interaction in formulation chemistry perspective. I have FTIR spectra of drug and excipients.

11 November 2013 7,693 6 View

Which method is used for chitosan nanoparticles coated with eudragit polymer for colon targeting i.e. before or after lyophilization of nanoparticles?

For uniform coating of nanoparticles by using various ratio of core and drug.

10 October 2013 7,212 0 View

Can anybody explain what is the methodology for coating of chitosan nano particles with pH responsive eudragit polymers?

Coating of ionic gelation nano particles.

08 August 2013 7,618 1 View