I'm searching about detection of antibiotic residues in eggs by HPLC. Currently there are different methods in articles. But I can't determine which one is practical.
The best solution for you depends on your available equipment, the specific antibiotic looked for and its concentration.
For LC-MS/MS read https://www.degruyter.com/downloadpdf/j/bvip.2012.56.issue-3/v10213-012-0057-6/v10213-012-0057-6.pdf
For usual HPLC read
Article EXTRACTION AND HPLC DETERMINATION OF OXYTETRACYCLINE IN MILK...
You probably need to look at two things;
1. The type of sample preparation and sample analysis equipment you have
2. The physicochemical properties of the antibiotics you want to determine. After all, you select your solvent depending on the properties of the analyte.
Dear Mahdi,
In my simple opinion, this depends on the type of sample preparation you use, the properties of the antibiotics and suitable solvent.
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