Hello,
I'm trying to get some mouse xenografts started for a gastric model that basically involves efficacy testing. What are some good human gastric cancer xenografts that give consistent tumors in nude mice with short latency?
We have several models (http://altogenlabs.com/xenograft-models/gastric-xenograft-model/) all of which have been successful. If you desire some kind of specific trait in the cells (whether it be a pattern of expression or whatnot) then you'll need to do some background research on each cell line and see what suits you best. If you've never done a xenograft with gastric cancer, contact us directly and we'd be happy to assist.
I've found some interesting papers that use NCI-N87. Is this a good cell line to use?
MKN28 and AZ521 are useful for xenograft experiments.
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Hi, Oliver,
I tried two cell lines, AGS and MKN74, to make a mouse xenograft model. Finally, only MKN74 cell line is good to make it. Please try this cell line with a number of 107 cells per mouse.
Best,
Liang
We have several models (http://altogenlabs.com/xenograft-models/gastric-xenograft-model/) all of which have been successful. If you desire some kind of specific trait in the cells (whether it be a pattern of expression or whatnot) then you'll need to do some background research on each cell line and see what suits you best. If you've never done a xenograft with gastric cancer, contact us directly and we'd be happy to assist.
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