Which mapping function is preferred for linkage map construction; Haldane's or Kosambi mapping function?

Which mapping function is preferred for linkage map construction; Haldane's or Kosambi mapping function? What are the effects of each one on the resulted linkage groups?

03 April 2020 8,390 2 View

Looking for pharmacologist interested in collaboration in a project "tubulin poly. inhibitors/stabilizers?

If anyone interested in collaborative work "design, synthesis and biological evaluation of small organic compounds with potential cytotoxic and tubulin polymerization inhibitory activity? in a...

11 March 2020 9,533 3 View

Anyone wants contribution in drawing graphs or pictures like this ....Please Contact me ?

Anyone wants contribution in drawing graphs like this ....Please Contact me see attached file ! Visit the research article of these pictures on my profile

26 April 2019 5,157 3 View

Protocol for double digestion with thermo scientific fast digest enzyme?

optimal reaction set up for double digest reaction with XhoI and EcoRI using my PCR product about 1600 bp and vector Pet 22 about 5500bp

04 April 2019 3,531 4 View

What is the best range of melting temp for primers?

I have designed a few sets of primer with a restriction site, most of them with tm 69-74 is this okay for PCR reaction

03 December 2018 941 6 View

Can Biofilms cause infections?

Biofilms are protective coatings that bacteria and fungus form to protect themselves from drug as antibiotic or anti-fungal treatment. So my question is: Can bacterial or fungal Biofilms cause...

15 November 2018 6,966 34 View

What is the cause of failure of detection of significant quantitive trait loci ?

excuse me for that as recently joined this field and trying to make my way. I have a data set of 1545 SNP markers from NGS for many traits of 63 individuals (F2 intercross) the genotypes analyzed...

28 March 2018 7,913 4 View

How to induce an epigenetic modification?

05 September 2016 9,919 3 View

Matching the participants in raw scores, standard scores or age equivalent?

02 August 2016 1,572 3 View

What is the best method to get rid of dicyclohexyl urea?

the by product generated upon using DCC

20 March 2015 4,104 2 View

How to code open-ended questions in SPSS?

Hello all, In SPSS I am going to code 2 open-ended questions. I have already read all the answers and I made a list of the most important categories to which I can code the answers. This question...

02 March 2021 1,757 4 View

How to eliminate Steady state error from Reinforcement learning genetic algorithm code?

The following code (see 1st 2 images attached) is used to produce PID controller values that are designed to control the system (G). The code finds the PID controller values (noted as k) by using...

28 February 2021 6,560 14 View

How could I process data in RCT to include it in meta-analysis?

I'm in the process of doing a meta-analysis and have encountered some problems with the RCT data. One of my outcom is muscle strength. In one study, I have three different measurements of muscle...

25 February 2021 7,603 3 View

Satellite orbit estimation using Recurrent Neural Network - what should I use?

Hello, I am a master's student studying in Yonsei Univeristy, Korea. I am trying to estimate the state of satellite, using Neural Network. Below is a simple flow of my study. 1. Train (t0 ~ t1)...

23 February 2021 6,383 3 View

Any Differences in COVID-19 vaccines?

Are there any differences (outside of the clinical trials that led to their EUA) observed in the rate of infection among those who have received the Pfizer vs Moderna vaccine since the mass...

22 February 2021 9,727 6 View

How can I get the coding gene sequences of Hela and U2OS cell lines? Is mRNA sequence of Hsp90 alpha tissue specific??

I am looking for hsp90 mRNA sequence in Hela and U2OS cell lines, I have tried through ncbi but always the output is hsp90 in homo sapiens not in the specific cell line. Kindly, could any one...

22 February 2021 1,853 3 View

How to constrain genetic algorithm input u?

My real system (buck converter) can only take an input of 0 to 1 (duty ratio) and I need to constrain the system so the controller action keeps within this bounds. How can I do this? The code for...

22 February 2021 2,125 3 View

Difficulty in debugging code to correct error - TypeError: '<' not supported ?

I am trying with a Unet code ontained from net ...in tensorflow. When trying to predict the segmentation result with the trained and saved model with metric " iou" using "CustomObjectScope"...

22 February 2021 5,254 1 View

The Role of Town Planners in CAV Use?

Colleagues and I are about to begin a project investigating the role of town planners and local authorities in establishing the introduction of connected and autonomous vehicles (CAVs). What...

21 February 2021 2,247 3 View

Looking for advices and tips to improve the staining and the gating strategy in human blood?

Hi, I am staining a human blood with CD19, CD3,CD14 and CD16. My gating strategy in FlowJo goes like this: - First, I gate a general population SSC-A VS FSC-A => Then gate for single cells, =>...

21 February 2021 5,724 4 View