It has been reported that PIC values range from 0-0.5 for dominant markers and 0-1 for co-dominant markers. However, some researchers have reported PIC values greater than 0.5 for dominant markers (ISSR, RAPD, etc.). Thus, what is the actual range of PIC?
Dear Dr. Pourkhaloee
For the dominant markers, the maximum PIC value is 0.5. Note, that for the markers with equal distribution in the population the PIC values are higher. The values are much higher for the markers with multiple alleles, however, the PIC value also depends on the distribution frequency of the alleles.
The maximum PIC value for dominant markers is 0.5, value above this may be due to the use of formula originally defined for a co-dominant marker.
For Co-dominant markers the PIC value increases with the increase of allele numbers. A co-dominant markers with two alleles have a maximum PIC value of 0.375.
There is no strong correlation of PIC value with number of alleles amplified. PIC may be less in markers having higher number of alleles amplified than those having less number of alleles amplified.
PIC range should be 0-1.0 for SSR markers. PIC value may vary with the diversity present in the germplasm. Same genotypes have different PIC values for the same set of markers cultivated in two different regions/environment.
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